Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 1000 | uM | 11058.143 | 0.2887 | 0.1754 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 5000 | uM | 11058.143 | 0.1516 | -0.1077 | 2.3374 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10695.143 | 0.9192 | 0.8735 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10695.143 | 0.9951 | 0.9925 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10695.143 | 0.9691 | 0.9519 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10695.143 | 0.9933 | 0.9895 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10695.143 | 1.0085 | 1.0132 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10695.143 | 0.9220 | 0.8779 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10695.143 | 0.7378 | 0.5798 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10695.143 | 0.5762 | 0.3042 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10695.143 | 0.3255 | -0.1624 | 1.2894 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 11852.143 | 1.0197 | 1.0321 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 11852.143 | 1.0567 | 1.0918 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 11852.143 | 0.9817 | 0.9702 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 11852.143 | 1.0443 | 1.0718 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 11852.143 | 1.0920 | 1.1485 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 11852.143 | 0.8853 | 0.8111 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 11852.143 | 0.7909 | 0.6522 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 11852.143 | 0.5184 | 0.1716 | 1.2284 | |
| SUM52PE | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 11852.143 | 0.3212 | -0.2066 | 1.2284 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10939.143 | 0.9257 | 0.9140 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10939.143 | 0.9441 | 0.9356 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10939.143 | 0.9620 | 0.9563 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10939.143 | 0.9121 | 0.8979 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10939.143 | 0.9312 | 0.9205 | 1.7568 |