Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7791.016 | 0.8831 | 0.7167 | 0.8138 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7791.016 | 0.8369 | 0.6071 | 0.8138 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7791.016 | 0.8452 | 0.6265 | 0.8138 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7791.016 | 0.2476 | -0.6402 | 0.8138 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9118.019 | 1.0271 | 1.0505 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9118.019 | 0.9895 | 0.9803 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9118.019 | 1.0251 | 1.0468 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9118.019 | 1.0056 | 1.0105 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9118.019 | 1.0101 | 1.0188 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9118.019 | 0.9418 | 0.8911 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9118.019 | 0.8948 | 0.8028 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9118.019 | 0.9982 | 0.9966 | 1.0707 | |
| 600MPE | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9118.019 | 0.8788 | 0.7726 | 1.0707 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7793.016 | 0.9211 | 0.8635 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7793.016 | 0.9841 | 0.9726 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7793.016 | 0.9337 | 0.8854 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7793.016 | 1.0132 | 1.0227 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7793.016 | 0.9848 | 0.9737 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7793.016 | 0.9763 | 0.9591 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7793.016 | 0.5849 | 0.2604 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7793.016 | 0.9155 | 0.8536 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7793.016 | 0.5848 | 0.2602 | 1.1616 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7794.016 | 0.9879 | 0.9875 | 1.9541 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7794.016 | 0.9557 | 0.9541 | 1.9541 | |
| AU565 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7794.016 | 1.0041 | 1.0042 | 1.9541 |