Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 12269.072 | 0.3772 | -0.1590 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 12269.072 | 0.9050 | 0.8302 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 12269.072 | 0.6713 | 0.4036 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 12269.072 | 0.4086 | -0.0969 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 12269.072 | 0.9985 | 0.9973 | 1.1256 | |
| SUM185PE | TNBC | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 12269.072 | 0.8072 | 0.6534 | 1.1256 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10579.072 | 0.9402 | 0.8763 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10579.072 | 1.0061 | 1.0126 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10579.072 | 1.0157 | 1.0326 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10579.072 | 0.9454 | 0.8869 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10579.072 | 0.9606 | 0.9184 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10579.072 | 0.9353 | 0.8661 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10579.072 | 1.0371 | 1.0769 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10579.072 | 0.8447 | 0.6791 | 0.9654 | |
| SUM225CWN | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10579.072 | 0.4322 | -0.1613 | 0.9654 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7535.072 | 0.9576 | 0.9222 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7535.072 | 0.9292 | 0.8699 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7535.072 | 0.9733 | 0.9511 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7535.072 | 1.0269 | 1.0492 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7535.072 | 0.9989 | 0.9979 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7535.072 | 1.0161 | 1.0295 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7535.072 | 1.0093 | 1.0169 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7535.072 | 0.8889 | 0.7955 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7535.072 | 0.6461 | 0.3408 | 1.0923 | |
| SUM229PE | TNBC | - | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 11058.072 | 0.9277 | 0.9359 | 2.3023 |