Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7493.073 | 0.9727 | 0.9612 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7493.073 | 1.0091 | 1.0128 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7493.073 | 0.9691 | 0.9560 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7493.073 | 0.0846 | -0.6522 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10997.072 | 0.9821 | 0.9736 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10997.072 | 0.9860 | 0.9794 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10997.072 | 1.0153 | 1.0224 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10997.072 | 1.0111 | 1.0163 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10997.072 | 0.9880 | 0.9823 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10997.072 | 1.0030 | 1.0044 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10997.072 | 0.9439 | 0.9169 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10997.072 | 1.0544 | 1.0795 | 1.3599 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10997.072 | 0.6755 | 0.4988 | 1.3599 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10419.072 | 0.9763 | 0.9219 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10419.072 | 0.9517 | 0.8425 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10419.072 | 0.9493 | 0.8349 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10419.072 | 0.9654 | 0.8868 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10419.072 | 0.9835 | 0.9455 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10419.072 | 0.9687 | 0.8974 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10419.072 | 0.9862 | 0.9544 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10419.072 | 0.9624 | 0.8770 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10419.072 | 0.5591 | -0.2362 | 0.6039 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10519.072 | 1.0105 | 1.0213 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10519.072 | 0.9507 | 0.9000 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10519.072 | 1.0351 | 1.0712 | 0.9861 |