Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7517.074 | 0.9296 | 0.9070 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7517.074 | 0.8879 | 0.8508 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7517.074 | 0.8879 | 0.8508 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7517.074 | 0.5538 | 0.3605 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7517.074 | 0.5538 | 0.3605 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7517.074 | 0.2275 | -0.2383 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7517.074 | 0.2275 | -0.2383 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7517.074 | 0.1387 | -0.4485 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7517.074 | 0.1387 | -0.4485 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7517.074 | 0.0947 | -0.5699 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7517.074 | 0.0947 | -0.5699 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7517.074 | 0.0695 | -0.6483 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7517.074 | 0.0695 | -0.6483 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7517.074 | 0.0688 | -0.6508 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7517.074 | 0.0688 | -0.6508 | 1.5337 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7518.074 | 0.9258 | 0.9071 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7518.074 | 0.9258 | 0.9071 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7518.074 | 0.9386 | 0.9233 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7518.074 | 0.9386 | 0.9233 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7518.074 | 1.0164 | 1.0202 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7518.074 | 1.0164 | 1.0202 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7518.074 | 0.6056 | 0.4676 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7518.074 | 0.6056 | 0.4676 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7518.074 | 0.2099 | -0.2368 | 1.6204 | |
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7518.074 | 0.2099 | -0.2368 | 1.6204 |