Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7454.072 | 0.9019 | 0.8507 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7454.072 | 0.8423 | 0.7579 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7455.072 | 0.9662 | 0.9434 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7455.072 | 0.8907 | 0.8156 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7455.072 | 0.7816 | 0.6278 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7455.072 | 0.8416 | 0.7315 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7455.072 | 0.8666 | 0.7745 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7455.072 | 0.8068 | 0.6714 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7455.072 | 0.9749 | 0.9580 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7455.072 | 0.8128 | 0.6819 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7455.072 | 0.6645 | 0.4213 | 1.1966 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7456.073 | 1.0454 | 1.0481 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7456.073 | 1.0192 | 1.0205 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7456.073 | 0.9969 | 0.9967 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7456.073 | 1.0505 | 1.0535 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7456.073 | 1.0486 | 1.0515 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7456.073 | 1.0112 | 1.0120 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7456.073 | 1.0377 | 1.0401 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7456.073 | 0.9818 | 0.9804 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7456.073 | 0.5134 | 0.3989 | 1.8650 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10469.072 | 1.0427 | 1.0632 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10469.072 | 1.0535 | 1.0792 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10469.072 | 0.9602 | 0.9405 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10469.072 | 1.1042 | 1.1530 | 1.3439 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10469.072 | 1.0380 | 1.0563 | 1.3439 |