Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10519.072 | 1.0032 | 1.0065 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10519.072 | 0.9847 | 0.9689 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10519.072 | 0.9780 | 0.9554 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10519.072 | 1.0265 | 1.0538 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10519.072 | 0.9895 | 0.9787 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10519.072 | 0.6092 | 0.2099 | 0.9861 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10998.072 | 0.9583 | 0.9067 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10998.072 | 0.9308 | 0.8453 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10998.072 | 0.9655 | 0.9227 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10998.072 | 0.9569 | 0.9034 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10998.072 | 0.9541 | 0.8972 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10998.072 | 0.9576 | 0.9050 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10998.072 | 0.9005 | 0.7780 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10998.072 | 1.0103 | 1.0232 | 0.8910 | |
| MDA-MB-134-VI | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10998.072 | 0.4968 | -0.0879 | 0.8910 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7496.072 | 1.0018 | 1.0041 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7496.072 | 0.9666 | 0.9243 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7496.072 | 1.0070 | 1.0158 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7496.072 | 0.9767 | 0.9471 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7496.072 | 0.9661 | 0.9232 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7496.072 | 0.9678 | 0.9270 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7496.072 | 0.9480 | 0.8823 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7496.072 | 0.8380 | 0.6364 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7496.072 | 0.0196 | -0.9770 | 0.8808 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7498.073 | 0.9977 | 0.9961 | 1.1962 |