Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7498.073 | 0.9566 | 0.9272 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7498.073 | 0.9889 | 0.9815 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7498.073 | 0.9997 | 0.9995 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7498.073 | 1.0018 | 1.0029 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7498.073 | 0.9991 | 0.9985 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7498.073 | 0.9470 | 0.9110 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7498.073 | 0.8883 | 0.8115 | 1.1962 | |
| MDA-MB-157 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7498.073 | 0.3196 | -0.2294 | 1.1962 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10642.072 | 1.0109 | 1.0404 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10642.072 | 0.9935 | 0.9760 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10642.072 | 1.0499 | 1.1887 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10642.072 | 0.9857 | 0.9475 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10642.072 | 1.0609 | 1.2312 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10642.072 | 1.0388 | 1.1459 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10642.072 | 1.0116 | 1.0430 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10642.072 | 0.9810 | 0.9304 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10642.072 | 0.7684 | 0.2283 | 0.5405 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10818.072 | 0.9525 | 0.7847 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10818.072 | 0.9225 | 0.6556 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10818.072 | 0.9619 | 0.8261 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10818.072 | 0.9415 | 0.7365 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10818.072 | 0.9223 | 0.6548 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10818.072 | 0.9451 | 0.7522 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10818.072 | 0.9160 | 0.6284 | 0.4268 | |
| MDA-MB-175-VII | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10818.072 | 0.8191 | 0.2531 | 0.4268 |