Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14771.203 | 0.1645 | -0.5915 | 1.1364 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7523.074 | 0.9803 | 0.9537 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7523.074 | 0.9803 | 0.9537 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7523.074 | 0.9708 | 0.9316 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7523.074 | 0.9708 | 0.9316 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7523.074 | 0.9937 | 0.9852 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7523.074 | 0.9937 | 0.9852 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7523.074 | 0.4099 | -0.2991 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7523.074 | 0.4099 | -0.2991 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7523.074 | 0.0169 | -0.9836 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7523.074 | 0.0169 | -0.9836 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7523.074 | 0.0068 | -0.9943 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7523.074 | 0.0068 | -0.9943 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7523.074 | 0.0037 | -0.9973 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7523.074 | 0.0037 | -0.9973 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7523.074 | 0.0077 | -0.9935 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7523.074 | 0.0077 | -0.9935 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7523.074 | 0.0057 | -0.9955 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 167 | uM | 7523.074 | 0.0057 | -0.9955 | 0.8505 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14918.203 | 0.9863 | 0.9485 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14918.203 | 0.9863 | 0.9485 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14918.203 | 0.9744 | 0.9045 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14918.203 | 0.9744 | 0.9045 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14918.203 | 0.9651 | 0.8703 | 0.5296 | |
| MX1 | Unknown | Unknown | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14918.203 | 0.9651 | 0.8703 | 0.5296 |