Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7500.074 | 0.6959 | 0.0064 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7500.074 | 0.9842 | 0.9404 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7500.074 | 0.9842 | 0.9404 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7500.074 | 1.0860 | 1.3384 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7500.074 | 1.0860 | 1.3384 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7500.074 | 0.6665 | -0.0726 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7500.074 | 0.6665 | -0.0726 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7500.074 | 0.3643 | -0.7047 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7500.074 | 0.3643 | -0.7047 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7500.074 | 0.2335 | -0.8728 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7500.074 | 0.2335 | -0.8728 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7500.074 | 0.1727 | -0.9282 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7500.074 | 0.1727 | -0.9282 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7500.074 | 0.0931 | -0.9778 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7500.074 | 0.0931 | -0.9778 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7500.074 | 0.0978 | -0.9755 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7500.074 | 0.0978 | -0.9755 | 0.5279 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14759.203 | 0.9835 | 0.9806 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14759.203 | 0.9835 | 0.9806 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14759.203 | 0.9357 | 0.9237 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14759.203 | 0.9357 | 0.9237 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14759.203 | 0.9668 | 0.9609 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14759.203 | 0.9668 | 0.9609 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14759.203 | 0.4698 | 0.2858 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14759.203 | 0.4698 | 0.2858 | 1.7099 |