Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7892.011 | 0.0766 | -0.2505 | 2.6182 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7896.011 | 0.9890 | 0.9798 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7896.011 | 0.9796 | 0.9625 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7896.011 | 1.0041 | 1.0076 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7896.011 | 1.0596 | 1.1091 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7896.011 | 1.0320 | 1.0586 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7896.011 | 0.9955 | 0.9918 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7896.011 | 0.7805 | 0.5935 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7896.011 | 0.4177 | -0.1019 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7896.011 | 0.1583 | -0.6310 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9648.011 | 0.9786 | 0.9385 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9648.011 | 1.0349 | 1.1017 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9648.011 | 1.0181 | 1.0525 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9648.011 | 0.9776 | 0.9356 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9648.011 | 0.9892 | 0.9688 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9648.011 | 0.9707 | 0.9159 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9648.011 | 0.7621 | 0.3506 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9648.011 | 0.4668 | -0.3349 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9648.011 | 0.1968 | -0.8091 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10095.021 | 0.9726 | 0.9403 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10095.021 | 0.9959 | 0.9910 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10095.021 | 0.9994 | 0.9987 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10095.021 | 1.0007 | 1.0015 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10095.021 | 0.9909 | 0.9802 | 0.9164 | |
| MDA-MB-361 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10095.021 | 0.9583 | 0.9092 | 0.9164 |