Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14759.203 | 0.0257 | -0.7649 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14759.203 | 0.0257 | -0.7649 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14759.203 | 0.0139 | -0.8361 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14759.203 | 0.0139 | -0.8361 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14759.203 | 0.0111 | -0.8565 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14759.203 | 0.0111 | -0.8565 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14759.203 | 0.0142 | -0.8342 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14759.203 | 0.0142 | -0.8342 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14759.203 | 0.0141 | -0.8345 | 1.7099 | |
| MDA-MB-175-VII | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14759.203 | 0.0141 | -0.8345 | 1.7099 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7504.074 | 1.0843 | 1.0872 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7504.074 | 1.0843 | 1.0872 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7504.074 | 1.1955 | 1.1975 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7504.074 | 1.1955 | 1.1975 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7504.074 | 1.0770 | 1.0798 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7504.074 | 1.0770 | 1.0798 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7504.074 | 0.9211 | 0.9152 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7504.074 | 0.9211 | 0.9152 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7504.074 | 0.0263 | -0.7063 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7504.074 | 0.0263 | -0.7063 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7504.074 | 0.0131 | -0.7964 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7504.074 | 0.0131 | -0.7964 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7504.074 | 0.0090 | -0.8329 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7504.074 | 0.0090 | -0.8329 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7504.074 | 0.0162 | -0.7726 | 1.8962 |