Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7504.074 | 0.0162 | -0.7726 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7504.074 | 0.0075 | -0.8488 | 1.8962 | |
| MDA-MB-231 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7504.074 | 0.0075 | -0.8488 | 1.8962 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7506.074 | 1.0023 | 1.0038 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7506.074 | 1.0023 | 1.0038 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7506.074 | 0.9804 | 0.9679 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7506.074 | 0.9804 | 0.9679 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7506.074 | 1.0283 | 1.0461 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7506.074 | 1.0283 | 1.0461 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7506.074 | 1.0666 | 1.1083 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7506.074 | 1.0666 | 1.1083 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7506.074 | 0.9723 | 0.9546 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7506.074 | 0.9723 | 0.9546 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7506.074 | 0.9455 | 0.9105 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7506.074 | 0.9455 | 0.9105 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7506.074 | 0.8952 | 0.8270 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7506.074 | 0.8952 | 0.8270 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7506.074 | 0.8721 | 0.7882 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7506.074 | 0.8721 | 0.7882 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7506.074 | 0.7706 | 0.6162 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7506.074 | 0.7706 | 0.6162 | 1.2231 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7507.074 | 1.0128 | 1.0306 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7507.074 | 1.0128 | 1.0306 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7507.074 | 1.0106 | 1.0255 | 0.8342 | |
| MDA-MB-361 | HER2amp | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7507.074 | 1.0106 | 1.0255 | 0.8342 |