Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7489.074 | 0.0530 | -0.4859 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7489.074 | 0.0530 | -0.4859 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7489.074 | 0.0089 | -0.7748 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7489.074 | 0.0089 | -0.7748 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7489.074 | 0.0049 | -0.8296 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7489.074 | 0.0049 | -0.8296 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7489.074 | 0.0039 | -0.8460 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7489.074 | 0.0039 | -0.8460 | 2.1617 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7490.074 | 0.9385 | 0.9534 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7490.074 | 0.9385 | 0.9534 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7490.074 | 0.9393 | 0.9540 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7490.074 | 0.9393 | 0.9540 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7490.074 | 0.9630 | 0.9722 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7490.074 | 0.9630 | 0.9722 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7490.074 | 0.9191 | 0.9383 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7490.074 | 0.9191 | 0.9383 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7490.074 | 0.5854 | 0.6392 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7490.074 | 0.5854 | 0.6392 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7490.074 | 0.4424 | 0.4772 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7490.074 | 0.4424 | 0.4772 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7490.074 | 0.2705 | 0.2304 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7490.074 | 0.2705 | 0.2304 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7490.074 | 0.0482 | -0.3521 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7490.074 | 0.0482 | -0.3521 | 2.6912 | |
MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7490.074 | 0.0179 | -0.5514 | 2.6912 |