Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
1.33
uM
7489.074
0.0530 -0.4859 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
1.33
uM
7489.074
0.0530 -0.4859 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
6.67
uM
7489.074
0.0089 -0.7748 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
6.67
uM
7489.074
0.0089 -0.7748 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
33.3
uM
7489.074
0.0049 -0.8296 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
33.3
uM
7489.074
0.0049 -0.8296 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
167
uM
7489.074
0.0039 -0.8460 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
167
uM
7489.074
0.0039 -0.8460 2.1617
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.000427
uM
7490.074
0.9385 0.9534 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.000427
uM
7490.074
0.9385 0.9534 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.00213
uM
7490.074
0.9393 0.9540 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.00213
uM
7490.074
0.9393 0.9540 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.0107
uM
7490.074
0.9630 0.9722 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.0107
uM
7490.074
0.9630 0.9722 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.0533
uM
7490.074
0.9191 0.9383 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.0533
uM
7490.074
0.9191 0.9383 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.267
uM
7490.074
0.5854 0.6392 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
0.267
uM
7490.074
0.5854 0.6392 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
1.33
uM
7490.074
0.4424 0.4772 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
1.33
uM
7490.074
0.4424 0.4772 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
6.67
uM
7490.074
0.2705 0.2304 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
6.67
uM
7490.074
0.2705 0.2304 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
33.3
uM
7490.074
0.0482 -0.3521 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
33.3
uM
7490.074
0.0482 -0.3521 2.6912
MCF12A
NM
Basal B
Bortezomib
Proteasome
Proteasome
167
uM
7490.074
0.0179 -0.5514 2.6912