Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 12254.072 | 0.9629 | 0.9615 | 1.9429 | |
| MCF 10F | NM | - | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 12254.072 | 1.0011 | 1.0011 | 1.9429 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7490.073 | 1.0338 | 1.0272 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7490.073 | 0.9293 | 0.9414 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7490.073 | 0.9878 | 0.9900 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7490.073 | 1.0095 | 1.0077 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7490.073 | 0.9636 | 0.9701 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7490.073 | 0.9776 | 0.9817 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7490.073 | 0.7544 | 0.7838 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7490.073 | 0.3117 | 0.2461 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7490.073 | 0.2955 | 0.2195 | 2.4641 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10817.072 | 1.0071 | 1.0087 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10817.072 | 0.8826 | 0.8520 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10817.072 | 0.9499 | 0.9377 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10817.072 | 0.9054 | 0.8813 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10817.072 | 0.9751 | 0.9692 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10817.072 | 0.9324 | 0.9156 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10817.072 | 0.9601 | 0.9505 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10817.072 | 0.4088 | 0.1532 | 1.6247 | |
| MCF12A | NM | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10817.072 | 0.2474 | -0.1534 | 1.6247 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7493.073 | 1.0368 | 1.0518 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7493.073 | 0.9737 | 0.9625 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7493.073 | 0.9780 | 0.9688 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7493.073 | 1.0261 | 1.0368 | 1.4116 | |
| MCF7 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7493.073 | 0.9978 | 0.9969 | 1.4116 |