Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 12239.072 | 1.0325 | 1.0311 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 12239.072 | 0.9950 | 0.9952 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 12239.072 | 1.0889 | 1.0839 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 12239.072 | 1.0003 | 1.0003 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 12239.072 | 0.9452 | 0.9464 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 12239.072 | 1.0406 | 1.0387 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 12239.072 | 0.8844 | 0.8848 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 12239.072 | 0.5197 | 0.4583 | 2.0720 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 12239.072 | 0.7084 | 0.6934 | 2.0720 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7453.073 | 1.0424 | 1.0609 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7453.073 | 1.0497 | 1.0713 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7453.073 | 1.0667 | 1.0955 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7453.073 | 1.0724 | 1.1036 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7453.073 | 1.0360 | 1.0518 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7453.073 | 1.0230 | 1.0331 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7453.073 | 1.0807 | 1.1154 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7453.073 | 0.7370 | 0.6041 | 1.3837 | |
| HCC1937 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7453.073 | 0.5203 | 0.2473 | 1.3837 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7454.072 | 0.9537 | 0.9300 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7454.072 | 0.8552 | 0.7781 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7454.072 | 0.8746 | 0.8083 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7454.072 | 0.8919 | 0.8352 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7454.072 | 0.9231 | 0.8832 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7454.072 | 0.9015 | 0.8500 | 1.3300 | |
| HCC1954 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7454.072 | 1.0034 | 1.0051 | 1.3300 |