Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10579.143 | 0.9203 | 0.7949 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10579.143 | 1.0225 | 1.0589 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10579.143 | 0.9423 | 0.8511 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10579.143 | 0.9643 | 0.9074 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 8 | uM | 10579.143 | 1.0865 | 1.2281 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 40 | uM | 10579.143 | 0.9444 | 0.8564 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 200 | uM | 10579.143 | 0.8766 | 0.6848 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 1000 | uM | 10579.143 | 0.6568 | 0.1567 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 5000 | uM | 10579.143 | 0.4109 | -0.3720 | 0.7678 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12098.143 | 0.9985 | 0.9968 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12098.143 | 1.0990 | 1.2018 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12098.143 | 0.9621 | 0.9229 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12098.143 | 0.9467 | 0.8915 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 8 | uM | 12098.143 | 0.9805 | 0.9602 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 40 | uM | 12098.143 | 0.8708 | 0.7371 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 200 | uM | 12098.143 | 0.7327 | 0.4570 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 1000 | uM | 12098.143 | 0.5756 | 0.1397 | 0.9820 | |
| SUM225CWN | HER2amp | Basal A | 5-DFUR | TYMS | TYMS | 5000 | uM | 12098.143 | 0.3425 | -0.3284 | 0.9820 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 11058.143 | 0.8850 | 0.8981 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 0.064 | uM | 11058.143 | 0.9547 | 0.9607 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 0.32 | uM | 11058.143 | 0.8912 | 0.9038 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 1.6 | uM | 11058.143 | 0.7692 | 0.7877 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 8 | uM | 11058.143 | 0.7629 | 0.7813 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 40 | uM | 11058.143 | 0.7393 | 0.7575 | 2.3374 | |
| SUM229PE | TNBC | - | 5-DFUR | TYMS | TYMS | 200 | uM | 11058.143 | 0.4466 | 0.4167 | 2.3374 |