Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10939.143 | 0.8223 | 0.7892 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10939.143 | 0.7103 | 0.6461 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10939.143 | 0.5220 | 0.3814 | 1.7568 | |
| T47D | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10939.143 | 0.4202 | 0.2209 | 1.7568 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12608.143 | 0.9606 | 0.9303 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.064 | uM | 12608.143 | 0.9626 | 0.9338 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 0.32 | uM | 12608.143 | 1.0292 | 1.0515 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12608.143 | 1.0450 | 1.0792 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 8 | uM | 12608.143 | 0.8667 | 0.7627 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 40 | uM | 12608.143 | 0.9234 | 0.8641 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 200 | uM | 12608.143 | 0.9020 | 0.8259 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 1000 | uM | 12608.143 | 0.8101 | 0.6605 | 1.1322 | |
| T47DKBLUC | Unknown | Unknown | 5-DFUR | TYMS | TYMS | 5000 | uM | 12608.143 | 0.5353 | 0.1517 | 1.1322 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10580.143 | 0.9300 | 0.8344 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10580.143 | 0.6733 | 0.2489 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10580.143 | 0.9840 | 0.9621 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10580.143 | 0.9100 | 0.7877 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10580.143 | 0.8992 | 0.7624 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10580.143 | 0.7938 | 0.5194 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10580.143 | 0.7074 | 0.3247 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10580.143 | 0.5898 | 0.0668 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10580.143 | 0.4635 | -0.1992 | 0.8402 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10754.143 | 0.9238 | 0.8729 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10754.143 | 0.9017 | 0.8357 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10754.143 | 0.8806 | 0.8000 | 1.2072 |