Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10754.143 | 1.0470 | 1.0776 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10754.143 | 0.9271 | 0.8785 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10754.143 | 0.7084 | 0.5032 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10754.143 | 0.6083 | 0.3249 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10754.143 | 0.4296 | -0.0068 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10754.143 | 0.3059 | -0.2503 | 1.2072 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 11938.143 | 1.0134 | 1.0513 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 11938.143 | 0.9856 | 0.9455 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 11938.143 | 1.0099 | 1.0377 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 11938.143 | 0.9863 | 0.9481 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 11938.143 | 0.7869 | 0.2677 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 11938.143 | 0.7283 | 0.0943 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 11938.143 | 0.7842 | 0.2595 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 11938.143 | 0.7678 | 0.2100 | 0.5258 | |
| UACC-812 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 11938.143 | 0.6053 | -0.2303 | 0.5258 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 11660.143 | 0.9587 | 0.9204 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 11660.143 | 0.9663 | 0.9350 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 11660.143 | 0.9145 | 0.8351 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 11660.143 | 0.7525 | 0.5212 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 11660.143 | 0.7192 | 0.4562 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 11660.143 | 0.6682 | 0.3567 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 11660.143 | 0.6241 | 0.2704 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 11660.143 | 0.5707 | 0.1656 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 11660.143 | 0.4850 | -0.0033 | 1.0389 | |
| ZR-75-1 | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12003.143 | 0.8637 | 0.7788 | 1.2499 |