Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7803.016 | 0.9846 | 0.9891 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7803.016 | 1.0146 | 1.0103 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7803.016 | 0.9387 | 0.9558 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7803.016 | 0.9604 | 0.9717 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7803.016 | 0.8915 | 0.9204 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7803.016 | 0.9220 | 0.9434 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7803.016 | 0.6728 | 0.7386 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7803.016 | 0.1323 | -0.0213 | 2.8300 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 7804.016 | 1.0418 | 1.0358 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 7804.016 | 0.9684 | 0.9724 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 7804.016 | 1.0026 | 1.0023 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 7804.016 | 0.9532 | 0.9589 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 7804.016 | 0.9438 | 0.9504 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 7804.016 | 0.9481 | 0.9543 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 7804.016 | 0.9151 | 0.9245 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 7804.016 | 0.8230 | 0.8380 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 167 | uM | 7804.016 | 0.0179 | -0.6510 | 2.3055 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.000427 | uM | 9024.016 | 1.0351 | 1.0214 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.00213 | uM | 9024.016 | 0.9444 | 0.9651 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0107 | uM | 9024.016 | 0.9602 | 0.9751 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.0533 | uM | 9024.016 | 0.9012 | 0.9369 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 0.267 | uM | 9024.016 | 0.9426 | 0.9639 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 1.33 | uM | 9024.016 | 0.9047 | 0.9392 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 6.67 | uM | 9024.016 | 0.8411 | 0.8961 | 3.2430 | |
| BT-549 | TNBC | Basal B | AG1478 | EGFR | ErbB | 33.3 | uM | 9024.016 | 0.5319 | 0.6462 | 3.2430 |