Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 9044.066 | 1.0138 | 1.0323 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 9044.066 | 1.0417 | 1.0978 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 9044.066 | 1.0136 | 1.0319 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 9044.066 | 1.0054 | 1.0127 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 9044.066 | 0.7371 | 0.4000 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 9044.066 | 0.6016 | 0.1040 | 0.8552 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 10381.066 | 1.0261 | 1.0359 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 10381.066 | 1.0036 | 1.0050 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 10381.066 | 0.9539 | 0.9358 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 10381.066 | 1.0151 | 1.0208 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 10381.066 | 1.0048 | 1.0066 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 10381.066 | 0.9593 | 0.9434 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 10381.066 | 1.0030 | 1.0041 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 10381.066 | 0.6031 | 0.4106 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 10381.066 | 0.4239 | 0.1059 | 1.4484 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7530.066 | 1.1131 | 1.1117 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.000427 | uM | 7530.066 | 0.9738 | 0.9732 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.00213 | uM | 7530.066 | 0.9847 | 0.9844 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0107 | uM | 7530.066 | 1.0391 | 1.0393 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0533 | uM | 7530.066 | 1.0610 | 1.0610 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.267 | uM | 7530.066 | 0.9715 | 0.9709 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 1.33 | uM | 7530.066 | 0.9789 | 0.9784 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 6.67 | uM | 7530.066 | 0.8455 | 0.8368 | 1.9710 | |
| SUM149PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 33.3 | uM | 7530.066 | 0.6421 | 0.5974 | 1.9710 | |
| SUM159PT | TNBC | Basal B | AG1024 | IGF1R | RTK | 0.0000853 | uM | 7531.066 | 1.0351 | 1.0209 | 3.3129 |