Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	5-DFUR	TYMS	TYMS	40	uM	12594.143	0.6983	0.5103	1.2787
MDA-MB-157	TNBC	Basal B	5-DFUR	TYMS	TYMS	200	uM	12594.143	0.7310	0.5653	1.2787
MDA-MB-157	TNBC	Basal B	5-DFUR	TYMS	TYMS	1000	uM	12594.143	0.5850	0.3151	1.2787
MDA-MB-157	TNBC	Basal B	5-DFUR	TYMS	TYMS	5000	uM	12594.143	0.4844	0.1345	1.2787
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.0128	uM	10642.143	0.9401	0.7708	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.064	uM	10642.143	0.8983	0.6190	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.32	uM	10642.143	0.9389	0.7665	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	1.6	uM	10642.143	0.8911	0.5937	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	8	uM	10642.143	0.9376	0.7615	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	40	uM	10642.143	0.7735	0.2059	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	200	uM	10642.143	0.7485	0.1303	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	1000	uM	10642.143	0.6744	-0.0797	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	5000	uM	10642.143	0.4705	-0.5472	0.5076
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.0128	uM	10818.143	0.9164	0.7396	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.064	uM	10818.143	0.9008	0.6927	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.32	uM	10818.143	0.9044	0.7035	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	1.6	uM	10818.143	0.8382	0.5087	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	8	uM	10818.143	0.8247	0.4703	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	40	uM	10818.143	0.8093	0.4267	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	200	uM	10818.143	0.7979	0.3947	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	1000	uM	10818.143	0.7178	0.1779	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	5000	uM	10818.143	0.4685	-0.4041	0.6263
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.0128	uM	12126.143	0.9566	0.8723	0.6729
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.064	uM	12126.143	0.9265	0.7854	0.6729
MDA-MB-175-VII	HR+	Luminal	5-DFUR	TYMS	TYMS	0.32	uM	12126.143	0.9328	0.8037	0.6729

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)