Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 12126.143 | 0.5940 | -0.0776 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 12126.143 | 0.5479 | -0.1822 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 12126.143 | 0.6193 | -0.0188 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 12126.143 | 0.6879 | 0.1471 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 12126.143 | 0.6385 | 0.0268 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 12126.143 | 0.4445 | -0.4005 | 0.6729 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10643.143 | 1.0150 | 1.0619 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10643.143 | 1.0209 | 1.0870 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10643.143 | 0.9345 | 0.7399 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10643.143 | 0.9558 | 0.8224 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10643.143 | 1.0179 | 1.0745 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10643.143 | 0.9408 | 0.7643 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10643.143 | 0.8890 | 0.5703 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10643.143 | 0.7940 | 0.2450 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10643.143 | 0.6308 | -0.2242 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 10999.143 | 0.9640 | 0.8641 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.064 | uM | 10999.143 | 1.0087 | 1.0336 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.32 | uM | 10999.143 | 0.9891 | 0.9584 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1.6 | uM | 10999.143 | 1.0014 | 1.0054 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 8 | uM | 10999.143 | 1.0094 | 1.0363 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 40 | uM | 10999.143 | 0.9841 | 0.9396 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 200 | uM | 10999.143 | 0.9795 | 0.9221 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 1000 | uM | 10999.143 | 0.7899 | 0.2725 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 5000 | uM | 10999.143 | 0.7229 | 0.0736 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | 5-DFUR | TYMS | TYMS | 0.0128 | uM | 12379.143 | 1.0214 | 1.0966 | 0.4493 |