Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7829.016 | 0.9624 | 0.9612 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7829.016 | 0.9087 | 0.9044 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7829.016 | 0.7138 | 0.6829 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7829.016 | 0.6418 | 0.5938 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7829.016 | 0.7051 | 0.6724 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7829.016 | 0.6160 | 0.5606 | 1.9532 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7830.016 | 0.9322 | 0.9321 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7830.016 | 0.8619 | 0.8589 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7830.016 | 0.9181 | 0.9176 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7830.016 | 0.8123 | 0.8055 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7830.016 | 0.8073 | 0.8000 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7830.016 | 0.5247 | 0.4559 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7830.016 | 0.6502 | 0.6181 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7830.016 | 0.5738 | 0.5215 | 2.0313 | |
| HCC1806 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7830.016 | 0.2081 | -0.0765 | 2.0313 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7832.016 | 1.0181 | 1.0288 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7832.016 | 1.0224 | 1.0355 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7832.016 | 0.9664 | 0.9464 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7832.016 | 0.9521 | 0.9235 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7832.016 | 0.9018 | 0.8423 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 1.33 | uM | 7832.016 | 0.9072 | 0.8510 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 6.67 | uM | 7832.016 | 0.8748 | 0.7983 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 33.3 | uM | 7832.016 | 0.5110 | 0.1732 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 167 | uM | 7832.016 | 0.1216 | -0.6250 | 1.2588 | |
| HCC1937 | TNBC | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7834.016 | 1.0007 | 1.0006 | 2.0442 |