Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14783.203 | 1.0462 | 1.0489 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14783.203 | 0.9575 | 0.9540 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14783.203 | 0.9575 | 0.9540 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14783.203 | 1.0137 | 1.0146 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14783.203 | 1.0137 | 1.0146 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14783.203 | 1.0030 | 1.0033 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14783.203 | 1.0030 | 1.0033 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14783.203 | 0.9397 | 0.9345 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14783.203 | 0.9397 | 0.9345 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14783.203 | 0.8069 | 0.7828 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14783.203 | 0.8069 | 0.7828 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14783.203 | 0.6765 | 0.6221 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14783.203 | 0.6765 | 0.6221 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14783.203 | 0.0304 | -0.6922 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14783.203 | 0.0304 | -0.6922 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14783.203 | 0.0124 | -0.8093 | 1.8667 | |
| 21NT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14783.203 | 0.0124 | -0.8093 | 1.8667 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14715.203 | 0.9530 | 0.9528 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14715.203 | 0.9530 | 0.9528 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14715.203 | 0.8818 | 0.8791 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14715.203 | 0.8818 | 0.8791 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14715.203 | 0.9474 | 0.9472 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14715.203 | 0.9474 | 0.9472 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14715.203 | 0.4327 | 0.3202 | 2.0168 | |
| 21PT | HER2amp | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14715.203 | 0.4327 | 0.3202 | 2.0168 |