LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | PF477736 | 0.04 | uM | LJP5 | 0.9091 | 0.0206 | 0.9035 | 0.0224 |
| MDA-MB-231 | PF477736 | 0.12 | uM | LJP5 | 0.9190 | 0.0464 | 0.9130 | 0.0501 |
| MDA-MB-231 | PF477736 | 0.37 | uM | LJP5 | 0.7730 | 0.0691 | 0.7467 | 0.0830 |
| MDA-MB-231 | PF477736 | 1.11 | uM | LJP5 | 0.6047 | 0.0923 | 0.5346 | 0.1217 |
| MDA-MB-231 | PF477736 | 3.33 | uM | LJP5 | 0.4380 | 0.0813 | 0.2968 | 0.1255 |
| MDA-MB-231 | PF477736 | 10 | uM | LJP5 | 0.2555 | 0.0363 | -0.0135 | 0.0797 |
| MDA-MB-231 | LDN-193189 | 0.04 | uM | LJP5 | 0.9976 | 0.0414 | 0.9962 | 0.0421 |
| MDA-MB-231 | LDN-193189 | 0.12 | uM | LJP5 | 0.9422 | 0.0459 | 0.9378 | 0.0483 |
| MDA-MB-231 | LDN-193189 | 0.37 | uM | LJP5 | 0.9306 | 0.0390 | 0.9252 | 0.0418 |
| MDA-MB-231 | LDN-193189 | 1.11 | uM | LJP5 | 0.7530 | 0.0263 | 0.7273 | 0.0323 |
| MDA-MB-231 | LDN-193189 | 3.33 | uM | LJP5 | 0.2970 | 0.1220 | 0.0105 | 0.2584 |
| MDA-MB-231 | LDN-193189 | 10 | uM | LJP5 | 0.1116 | 0.0083 | -0.3545 | 0.0218 |
| MDA-MB-231 | PF431396 | 0.04 | uM | LJP5 | 0.9182 | 0.0308 | 0.9134 | 0.0334 |
| MDA-MB-231 | PF431396 | 0.12 | uM | LJP5 | 0.7984 | 0.0396 | 0.7796 | 0.0475 |
| MDA-MB-231 | PF431396 | 0.37 | uM | LJP5 | 0.5711 | 0.0800 | 0.4902 | 0.1170 |
| MDA-MB-231 | PF431396 | 1.11 | uM | LJP5 | 0.3981 | 0.0449 | 0.2412 | 0.0764 |
| MDA-MB-231 | PF431396 | 3.33 | uM | LJP5 | 0.3204 | 0.0388 | 0.1100 | 0.0727 |
| MDA-MB-231 | PF431396 | 10 | uM | LJP5 | 0.1764 | 0.0478 | -0.1965 | 0.1246 |
| MDA-MB-231 | Celastrol | 0.04 | uM | LJP6 | 1.0805 | 0.0359 | 1.0833 | 0.0389 |
| MDA-MB-231 | Celastrol | 0.12 | uM | LJP6 | 1.0448 | 0.0191 | 1.0459 | 0.0202 |
| MDA-MB-231 | Celastrol | 0.37 | uM | LJP6 | 0.7489 | 0.0933 | 0.7179 | 0.1059 |
| MDA-MB-231 | Celastrol | 1.11 | uM | LJP6 | 0.3147 | 0.0956 | 0.0718 | 0.1707 |
| MDA-MB-231 | Celastrol | 3.33 | uM | LJP6 | 0.2055 | 0.0202 | -0.1237 | 0.0526 |
| MDA-MB-231 | Celastrol | 10 | uM | LJP6 | 0.1125 | 0.0308 | -0.3706 | 0.1065 |
| MDA-MB-231 | SU11274 | 0.04 | uM | LJP5 | 1.0705 | 0.0385 | 1.0698 | 0.0376 |