LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | R406 | 0.37 | uM | LJP6 | 0.9081 | 0.0372 | 0.9024 | 0.0382 |
| MDA-MB-231 | R406 | 1.11 | uM | LJP6 | 0.8424 | 0.0349 | 0.8282 | 0.0344 |
| MDA-MB-231 | R406 | 3.33 | uM | LJP6 | 0.6899 | 0.0179 | 0.6476 | 0.0200 |
| MDA-MB-231 | R406 | 10 | uM | LJP6 | 0.3815 | 0.0517 | 0.2027 | 0.1027 |
| MDA-MB-231 | BI-2536 | 0.04 | uM | LJP6 | 0.2739 | 0.0300 | 0.0155 | 0.0784 |
| MDA-MB-231 | BI-2536 | 0.12 | uM | LJP6 | 0.2694 | 0.0211 | 0.0087 | 0.0609 |
| MDA-MB-231 | BI-2536 | 0.37 | uM | LJP6 | 0.2692 | 0.0309 | 0.0057 | 0.0785 |
| MDA-MB-231 | BI-2536 | 1.11 | uM | LJP6 | 0.2789 | 0.0331 | 0.0242 | 0.0820 |
| MDA-MB-231 | BI-2536 | 3.33 | uM | LJP6 | 0.2800 | 0.0255 | 0.0274 | 0.0676 |
| MDA-MB-231 | BI-2536 | 10 | uM | LJP6 | 0.2453 | 0.0590 | -0.0537 | 0.1450 |
| MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 0.6526 | 0.1443 | 0.5865 | 0.1852 |
| MDA-MB-231 | A443654 | 0.12 | uM | LJP6 | 0.4764 | 0.1084 | 0.3445 | 0.1531 |
| MDA-MB-231 | A443654 | 0.37 | uM | LJP6 | 0.2575 | 0.0586 | -0.0255 | 0.1257 |
| MDA-MB-231 | A443654 | 1.11 | uM | LJP6 | 0.1771 | 0.0325 | -0.1960 | 0.0921 |
| MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 0.1613 | 0.0390 | -0.2376 | 0.1110 |
| MDA-MB-231 | A443654 | 10 | uM | LJP6 | 0.1188 | 0.0338 | -0.3512 | 0.1150 |
| MDA-MB-231 | SB590885 | 0.04 | uM | LJP5 | 0.9954 | 0.0078 | 0.9939 | 0.0078 |
| MDA-MB-231 | SB590885 | 0.12 | uM | LJP5 | 0.9764 | 0.0342 | 0.9737 | 0.0359 |
| MDA-MB-231 | SB590885 | 0.37 | uM | LJP5 | 0.8951 | 0.0469 | 0.8874 | 0.0505 |
| MDA-MB-231 | SB590885 | 1.11 | uM | LJP5 | 0.8305 | 0.0796 | 0.8140 | 0.0905 |
| MDA-MB-231 | SB590885 | 3.33 | uM | LJP5 | 0.7411 | 0.0895 | 0.7083 | 0.1075 |
| MDA-MB-231 | SB590885 | 10 | uM | LJP5 | 0.1706 | 0.0563 | -0.2229 | 0.1600 |
| MDA-MB-231 | Pictilisib | 0.04 | uM | LJP6 | 0.8016 | 0.0514 | 0.7837 | 0.0531 |
| MDA-MB-231 | Pictilisib | 0.12 | uM | LJP6 | 0.8130 | 0.0396 | 0.7966 | 0.0399 |
| MDA-MB-231 | Pictilisib | 0.37 | uM | LJP6 | 0.7440 | 0.0054 | 0.7149 | 0.0066 |