LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | PD0325901 | 10 | uM | LJP6 | 0.2074 | 0.0320 | -0.1302 | 0.0966 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP5 | 0.5569 | 0.1010 | 0.4661 | 0.1368 |
| MDA-MB-231 | Geldanamycin | 0.04 | uM | LJP6 | 0.5265 | 0.0851 | 0.4191 | 0.1229 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP5 | 0.3063 | 0.0250 | 0.0858 | 0.0518 |
| MDA-MB-231 | Geldanamycin | 0.12 | uM | LJP6 | 0.3008 | 0.0277 | 0.0667 | 0.0716 |
| MDA-MB-231 | Geldanamycin | 0.37 | uM | LJP5 | 0.2730 | 0.0476 | 0.0182 | 0.0964 |
| MDA-MB-231 | Geldanamycin | 0.37 | uM | LJP6 | 0.2745 | 0.0513 | 0.0102 | 0.1177 |
| MDA-MB-231 | Geldanamycin | 1.11 | uM | LJP5 | 0.2415 | 0.0381 | -0.0429 | 0.0837 |
| MDA-MB-231 | Geldanamycin | 1.11 | uM | LJP6 | 0.2361 | 0.0514 | -0.0701 | 0.1290 |
| MDA-MB-231 | Geldanamycin | 3.33 | uM | LJP5 | 0.1983 | 0.0280 | -0.1339 | 0.0675 |
| MDA-MB-231 | Geldanamycin | 3.33 | uM | LJP6 | 0.1943 | 0.0405 | -0.1614 | 0.1148 |
| MDA-MB-231 | Geldanamycin | 10 | uM | LJP5 | 0.1494 | 0.0178 | -0.2507 | 0.0536 |
| MDA-MB-231 | Geldanamycin | 10 | uM | LJP6 | 0.1310 | 0.0280 | -0.3175 | 0.1037 |
| MDA-MB-231 | YM 201636 | 0.04 | uM | LJP5 | 1.0390 | 0.0185 | 1.0382 | 0.0185 |
| MDA-MB-231 | YM 201636 | 0.12 | uM | LJP5 | 0.9590 | 0.0310 | 0.9543 | 0.0336 |
| MDA-MB-231 | YM 201636 | 0.37 | uM | LJP5 | 0.8798 | 0.0406 | 0.8693 | 0.0473 |
| MDA-MB-231 | YM 201636 | 1.11 | uM | LJP5 | 0.7718 | 0.0430 | 0.7468 | 0.0542 |
| MDA-MB-231 | YM 201636 | 3.33 | uM | LJP5 | 0.6978 | 0.0614 | 0.6573 | 0.0806 |
| MDA-MB-231 | YM 201636 | 10 | uM | LJP5 | 0.3177 | 0.0776 | 0.0924 | 0.1408 |
| MDA-MB-231 | TWS119 | 0.04 | uM | LJP5 | 0.9782 | 0.0292 | 0.9747 | 0.0322 |
| MDA-MB-231 | TWS119 | 0.12 | uM | LJP5 | 0.9648 | 0.0380 | 0.9608 | 0.0407 |
| MDA-MB-231 | TWS119 | 0.37 | uM | LJP5 | 0.9346 | 0.0448 | 0.9293 | 0.0484 |
| MDA-MB-231 | TWS119 | 1.11 | uM | LJP5 | 0.8028 | 0.0270 | 0.7850 | 0.0323 |
| MDA-MB-231 | TWS119 | 3.33 | uM | LJP5 | 0.6651 | 0.0082 | 0.6191 | 0.0121 |
| MDA-MB-231 | TWS119 | 10 | uM | LJP5 | 0.2790 | 0.0142 | 0.0363 | 0.0254 |