LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | SU11274 | 0.12 | uM | LJP5 | 1.0130 | 0.0225 | 1.0120 | 0.0232 |
| MDA-MB-231 | SU11274 | 0.37 | uM | LJP5 | 1.0030 | 0.0315 | 1.0015 | 0.0326 |
| MDA-MB-231 | SU11274 | 1.11 | uM | LJP5 | 0.9574 | 0.0310 | 0.9544 | 0.0334 |
| MDA-MB-231 | SU11274 | 3.33 | uM | LJP5 | 0.8581 | 0.0378 | 0.8467 | 0.0437 |
| MDA-MB-231 | SU11274 | 10 | uM | LJP5 | 0.3141 | 0.0354 | 0.0987 | 0.0711 |
| MDA-MB-231 | Canertinib | 0.04 | uM | LJP6 | 1.0415 | 0.0185 | 1.0412 | 0.0170 |
| MDA-MB-231 | Canertinib | 0.12 | uM | LJP6 | 0.9670 | 0.0089 | 0.9653 | 0.0086 |
| MDA-MB-231 | Canertinib | 0.37 | uM | LJP6 | 0.9141 | 0.0151 | 0.9087 | 0.0150 |
| MDA-MB-231 | Canertinib | 1.11 | uM | LJP6 | 0.8019 | 0.0155 | 0.7817 | 0.0198 |
| MDA-MB-231 | Canertinib | 3.33 | uM | LJP6 | 0.6323 | 0.0376 | 0.5722 | 0.0573 |
| MDA-MB-231 | Canertinib | 10 | uM | LJP6 | 0.1528 | 0.0100 | -0.2494 | 0.0445 |
| MDA-MB-231 | NVP-AEW541 | 0.04 | uM | LJP5 | 1.0125 | 0.0232 | 1.0129 | 0.0241 |
| MDA-MB-231 | NVP-AEW541 | 0.12 | uM | LJP5 | 1.0032 | 0.0268 | 1.0032 | 0.0278 |
| MDA-MB-231 | NVP-AEW541 | 0.37 | uM | LJP5 | 0.9954 | 0.0313 | 0.9942 | 0.0320 |
| MDA-MB-231 | NVP-AEW541 | 1.11 | uM | LJP5 | 0.9635 | 0.0338 | 0.9613 | 0.0359 |
| MDA-MB-231 | NVP-AEW541 | 3.33 | uM | LJP5 | 0.9656 | 0.0146 | 0.9642 | 0.0154 |
| MDA-MB-231 | NVP-AEW541 | 10 | uM | LJP5 | 0.3743 | 0.0459 | 0.1982 | 0.0852 |
| MDA-MB-231 | PHA-665752 | 0.04 | uM | LJP5 | 1.0271 | 0.0255 | 1.0277 | 0.0262 |
| MDA-MB-231 | PHA-665752 | 0.12 | uM | LJP5 | 1.0250 | 0.0399 | 1.0244 | 0.0397 |
| MDA-MB-231 | PHA-665752 | 0.37 | uM | LJP5 | 1.0217 | 0.0245 | 1.0216 | 0.0246 |
| MDA-MB-231 | PHA-665752 | 1.11 | uM | LJP5 | 0.9979 | 0.0304 | 0.9972 | 0.0308 |
| MDA-MB-231 | PHA-665752 | 3.33 | uM | LJP5 | 0.9424 | 0.0123 | 0.9399 | 0.0131 |
| MDA-MB-231 | PHA-665752 | 10 | uM | LJP5 | 0.1289 | 0.0509 | -0.3426 | 0.1749 |
| MDA-MB-231 | PI103 | 0.04 | uM | LJP6 | 0.7938 | 0.0328 | 0.7715 | 0.0433 |
| MDA-MB-231 | PI103 | 0.12 | uM | LJP6 | 0.6828 | 0.0421 | 0.6370 | 0.0596 |