LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MDA-MB-231 | Radicicol | 0.37 | uM | LJP5 | 0.4310 | 0.0366 | 0.2943 | 0.0610 |
MDA-MB-231 | Radicicol | 0.37 | uM | LJP6 | 0.4420 | 0.0466 | 0.3021 | 0.0874 |
MDA-MB-231 | Radicicol | 1.11 | uM | LJP5 | 0.2883 | 0.0371 | 0.0499 | 0.0784 |
MDA-MB-231 | Radicicol | 1.11 | uM | LJP6 | 0.3179 | 0.0264 | 0.0982 | 0.0679 |
MDA-MB-231 | Radicicol | 3.33 | uM | LJP5 | 0.2523 | 0.0382 | -0.0210 | 0.0809 |
MDA-MB-231 | Radicicol | 3.33 | uM | LJP6 | 0.2832 | 0.0381 | 0.0318 | 0.0892 |
MDA-MB-231 | Radicicol | 10 | uM | LJP5 | 0.2502 | 0.0266 | -0.0222 | 0.0599 |
MDA-MB-231 | Radicicol | 10 | uM | LJP6 | 0.2476 | 0.0322 | -0.0375 | 0.0873 |
MDA-MB-231 | Withaferin A | 0.04 | uM | LJP5 | 1.0620 | 0.0394 | 1.0617 | 0.0385 |
MDA-MB-231 | Withaferin A | 0.04 | uM | LJP6 | 1.0171 | 0.0171 | 1.0178 | 0.0186 |
MDA-MB-231 | Withaferin A | 0.12 | uM | LJP5 | 1.0219 | 0.0379 | 1.0218 | 0.0391 |
MDA-MB-231 | Withaferin A | 0.12 | uM | LJP6 | 0.9824 | 0.0094 | 0.9810 | 0.0106 |
MDA-MB-231 | Withaferin A | 0.37 | uM | LJP5 | 0.7010 | 0.0754 | 0.6596 | 0.0923 |
MDA-MB-231 | Withaferin A | 0.37 | uM | LJP6 | 0.6304 | 0.0784 | 0.5677 | 0.0977 |
MDA-MB-231 | Withaferin A | 1.11 | uM | LJP5 | 0.2541 | 0.0198 | -0.0135 | 0.0466 |
MDA-MB-231 | Withaferin A | 1.11 | uM | LJP6 | 0.2376 | 0.0125 | -0.0541 | 0.0343 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP5 | 0.2049 | 0.0121 | -0.1171 | 0.0320 |
MDA-MB-231 | Withaferin A | 3.33 | uM | LJP6 | 0.1863 | 0.0119 | -0.1682 | 0.0304 |
MDA-MB-231 | Withaferin A | 10 | uM | LJP5 | 0.1203 | 0.0146 | -0.3298 | 0.0441 |
MDA-MB-231 | Withaferin A | 10 | uM | LJP6 | 0.1207 | 0.0223 | -0.3424 | 0.0770 |
BT-20 | Seliciclib | 0.04 | uM | LJP5 | 1.0186 | 0.0024 | 1.0218 | 0.0024 |
BT-20 | Seliciclib | 0.12 | uM | LJP5 | 0.9975 | 0.0017 | 0.9967 | 0.0020 |
BT-20 | Seliciclib | 0.37 | uM | LJP5 | 0.9254 | 0.0161 | 0.9128 | 0.0166 |
BT-20 | Seliciclib | 1.11 | uM | LJP5 | 0.8679 | 0.0430 | 0.8439 | 0.0484 |
BT-20 | Seliciclib | 3.33 | uM | LJP5 | 0.8013 | 0.0341 | 0.7588 | 0.0360 |