LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Alpelisib | 1.11 | uM | LJP5 | 0.9383 | 0.0167 | 0.9347 | 0.0187 |
| MDA-MB-231 | Alpelisib | 3.33 | uM | LJP5 | 0.8959 | 0.0089 | 0.8899 | 0.0085 |
| MDA-MB-231 | Alpelisib | 10 | uM | LJP5 | 0.6892 | 0.0445 | 0.6504 | 0.0521 |
| MDA-MB-231 | GDC-0980 | 0.04 | uM | LJP5 | 0.7336 | 0.0322 | 0.7047 | 0.0395 |
| MDA-MB-231 | GDC-0980 | 0.12 | uM | LJP5 | 0.6409 | 0.0501 | 0.5877 | 0.0675 |
| MDA-MB-231 | GDC-0980 | 0.37 | uM | LJP5 | 0.5229 | 0.0455 | 0.4296 | 0.0696 |
| MDA-MB-231 | GDC-0980 | 1.11 | uM | LJP5 | 0.4409 | 0.0386 | 0.3092 | 0.0658 |
| MDA-MB-231 | GDC-0980 | 3.33 | uM | LJP5 | 0.4006 | 0.0351 | 0.2464 | 0.0631 |
| MDA-MB-231 | GDC-0980 | 10 | uM | LJP5 | 0.3461 | 0.0426 | 0.1540 | 0.0794 |
| MDA-MB-231 | Mitoxantrone | 0.04 | uM | LJP5 | 0.2376 | 0.0099 | -0.0456 | 0.0260 |
| MDA-MB-231 | Mitoxantrone | 0.04 | uM | LJP6 | 0.2325 | 0.0122 | -0.0647 | 0.0453 |
| MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP5 | 0.2382 | 0.0191 | -0.0450 | 0.0458 |
| MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP6 | 0.2244 | 0.0123 | -0.0818 | 0.0474 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 0.1996 | 0.0217 | -0.1292 | 0.0553 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 0.1970 | 0.0222 | -0.1441 | 0.0724 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 0.1658 | 0.0350 | -0.2160 | 0.0984 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 0.1632 | 0.0302 | -0.2285 | 0.0990 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 0.1355 | 0.0484 | -0.3149 | 0.1582 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 0.1264 | 0.0408 | -0.3389 | 0.1469 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 0.0901 | 0.0395 | -0.4565 | 0.1543 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 0.0733 | 0.0260 | -0.5038 | 0.1167 |
| MDA-MB-231 | Radicicol | 0.04 | uM | LJP5 | 1.0502 | 0.0208 | 1.0503 | 0.0202 |
| MDA-MB-231 | Radicicol | 0.04 | uM | LJP6 | 1.0762 | 0.0240 | 1.0765 | 0.0217 |
| MDA-MB-231 | Radicicol | 0.12 | uM | LJP5 | 0.7722 | 0.0342 | 0.7490 | 0.0405 |
| MDA-MB-231 | Radicicol | 0.12 | uM | LJP6 | 0.7656 | 0.0558 | 0.7385 | 0.0652 |