LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | CHIR-99021 | 0.37 | uM | LJP6 | 0.8435 | 0.0134 | 0.8306 | 0.0122 |
| MDA-MB-231 | CHIR-99021 | 1.11 | uM | LJP6 | 0.8407 | 0.0308 | 0.8267 | 0.0353 |
| MDA-MB-231 | CHIR-99021 | 3.33 | uM | LJP6 | 0.8444 | 0.0148 | 0.8314 | 0.0140 |
| MDA-MB-231 | CHIR-99021 | 10 | uM | LJP6 | 0.7845 | 0.0153 | 0.7617 | 0.0205 |
| MDA-MB-231 | Linifanib | 0.04 | uM | LJP6 | 1.0802 | 0.0108 | 1.0814 | 0.0083 |
| MDA-MB-231 | Linifanib | 0.12 | uM | LJP6 | 1.0866 | 0.0201 | 1.0870 | 0.0173 |
| MDA-MB-231 | Linifanib | 0.37 | uM | LJP6 | 1.0781 | 0.0292 | 1.0778 | 0.0261 |
| MDA-MB-231 | Linifanib | 1.11 | uM | LJP6 | 1.0709 | 0.0290 | 1.0721 | 0.0304 |
| MDA-MB-231 | Linifanib | 3.33 | uM | LJP6 | 1.0555 | 0.0259 | 1.0562 | 0.0258 |
| MDA-MB-231 | Linifanib | 10 | uM | LJP6 | 0.3820 | 0.0924 | 0.1918 | 0.1681 |
| MDA-MB-231 | PIK-93 | 0.04 | uM | LJP5 | 1.0112 | 0.0305 | 1.0097 | 0.0317 |
| MDA-MB-231 | PIK-93 | 0.12 | uM | LJP5 | 1.0136 | 0.0341 | 1.0111 | 0.0351 |
| MDA-MB-231 | PIK-93 | 0.37 | uM | LJP5 | 1.0039 | 0.0565 | 0.9989 | 0.0591 |
| MDA-MB-231 | PIK-93 | 1.11 | uM | LJP5 | 0.9244 | 0.0318 | 0.9190 | 0.0355 |
| MDA-MB-231 | PIK-93 | 3.33 | uM | LJP5 | 0.7975 | 0.0194 | 0.7795 | 0.0207 |
| MDA-MB-231 | PIK-93 | 10 | uM | LJP5 | 0.4150 | 0.0052 | 0.2724 | 0.0122 |
| MDA-MB-231 | Dactolisib | 0.04 | uM | LJP5 | 0.5039 | 0.0732 | 0.3966 | 0.1145 |
| MDA-MB-231 | Dactolisib | 0.12 | uM | LJP5 | 0.4393 | 0.0647 | 0.3011 | 0.1086 |
| MDA-MB-231 | Dactolisib | 0.37 | uM | LJP5 | 0.3739 | 0.0622 | 0.1957 | 0.1128 |
| MDA-MB-231 | Dactolisib | 1.11 | uM | LJP5 | 0.3839 | 0.0483 | 0.2163 | 0.0875 |
| MDA-MB-231 | Dactolisib | 3.33 | uM | LJP5 | 0.3862 | 0.0354 | 0.2232 | 0.0646 |
| MDA-MB-231 | Dactolisib | 10 | uM | LJP5 | 0.4124 | 0.0307 | 0.2663 | 0.0547 |
| MDA-MB-231 | Alpelisib | 0.04 | uM | LJP5 | 0.9994 | 0.0310 | 0.9971 | 0.0336 |
| MDA-MB-231 | Alpelisib | 0.12 | uM | LJP5 | 0.9879 | 0.0206 | 0.9856 | 0.0223 |
| MDA-MB-231 | Alpelisib | 0.37 | uM | LJP5 | 0.9661 | 0.0257 | 0.9630 | 0.0276 |