LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
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MDA-MB-231 | Pictilisib | 1.11 | uM | LJP6 | 0.7132 | 0.0216 | 0.6764 | 0.0321 |
MDA-MB-231 | Pictilisib | 3.33 | uM | LJP6 | 0.6871 | 0.0171 | 0.6438 | 0.0308 |
MDA-MB-231 | Pictilisib | 10 | uM | LJP6 | 0.4865 | 0.0314 | 0.3722 | 0.0597 |
MDA-MB-231 | PD184352 | 0.04 | uM | LJP5 | 0.9932 | 0.0325 | 0.9916 | 0.0337 |
MDA-MB-231 | PD184352 | 0.12 | uM | LJP5 | 0.8632 | 0.0043 | 0.8538 | 0.0043 |
MDA-MB-231 | PD184352 | 0.37 | uM | LJP5 | 0.7884 | 0.0131 | 0.7697 | 0.0133 |
MDA-MB-231 | PD184352 | 1.11 | uM | LJP5 | 0.6727 | 0.0287 | 0.6303 | 0.0329 |
MDA-MB-231 | PD184352 | 3.33 | uM | LJP5 | 0.5817 | 0.0248 | 0.5129 | 0.0289 |
MDA-MB-231 | PD184352 | 10 | uM | LJP5 | 0.3598 | 0.0261 | 0.1805 | 0.0505 |
MDA-MB-231 | PLX-4720 | 0.04 | uM | LJP5 | 0.9912 | 0.0325 | 0.9887 | 0.0347 |
MDA-MB-231 | PLX-4720 | 0.12 | uM | LJP5 | 1.0086 | 0.0301 | 1.0073 | 0.0311 |
MDA-MB-231 | PLX-4720 | 0.37 | uM | LJP5 | 1.0043 | 0.0169 | 1.0026 | 0.0183 |
MDA-MB-231 | PLX-4720 | 1.11 | uM | LJP5 | 0.9323 | 0.0224 | 0.9286 | 0.0235 |
MDA-MB-231 | PLX-4720 | 3.33 | uM | LJP5 | 0.8368 | 0.0380 | 0.8221 | 0.0423 |
MDA-MB-231 | PLX-4720 | 10 | uM | LJP5 | 0.6793 | 0.0972 | 0.6296 | 0.1216 |
MDA-MB-231 | Lapatinib | 0.04 | uM | LJP6 | 0.8854 | 0.0201 | 0.8778 | 0.0189 |
MDA-MB-231 | Lapatinib | 0.12 | uM | LJP6 | 0.9418 | 0.0045 | 0.9385 | 0.0045 |
MDA-MB-231 | Lapatinib | 0.37 | uM | LJP6 | 0.9568 | 0.0070 | 0.9548 | 0.0060 |
MDA-MB-231 | Lapatinib | 1.11 | uM | LJP6 | 0.9518 | 0.0127 | 0.9484 | 0.0147 |
MDA-MB-231 | Lapatinib | 3.33 | uM | LJP6 | 0.9499 | 0.0065 | 0.9473 | 0.0066 |
MDA-MB-231 | Lapatinib | 10 | uM | LJP6 | 0.6700 | 0.0417 | 0.6199 | 0.0631 |
MDA-MB-231 | Sirolimus | 0.04 | uM | LJP6 | 0.8192 | 0.0232 | 0.8020 | 0.0283 |
MDA-MB-231 | Sirolimus | 0.12 | uM | LJP6 | 0.8001 | 0.0217 | 0.7812 | 0.0227 |
MDA-MB-231 | Sirolimus | 0.37 | uM | LJP6 | 0.8287 | 0.0212 | 0.8122 | 0.0280 |
MDA-MB-231 | Sirolimus | 1.11 | uM | LJP6 | 0.8047 | 0.0243 | 0.7866 | 0.0245 |