LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MDA-MB-231 Pictilisib
1.11
uM
LJP6
0.7132 0.0216 0.6764 0.0321
MDA-MB-231 Pictilisib
3.33
uM
LJP6
0.6871 0.0171 0.6438 0.0308
MDA-MB-231 Pictilisib
10
uM
LJP6
0.4865 0.0314 0.3722 0.0597
MDA-MB-231 PD184352
0.04
uM
LJP5
0.9932 0.0325 0.9916 0.0337
MDA-MB-231 PD184352
0.12
uM
LJP5
0.8632 0.0043 0.8538 0.0043
MDA-MB-231 PD184352
0.37
uM
LJP5
0.7884 0.0131 0.7697 0.0133
MDA-MB-231 PD184352
1.11
uM
LJP5
0.6727 0.0287 0.6303 0.0329
MDA-MB-231 PD184352
3.33
uM
LJP5
0.5817 0.0248 0.5129 0.0289
MDA-MB-231 PD184352
10
uM
LJP5
0.3598 0.0261 0.1805 0.0505
MDA-MB-231 PLX-4720
0.04
uM
LJP5
0.9912 0.0325 0.9887 0.0347
MDA-MB-231 PLX-4720
0.12
uM
LJP5
1.0086 0.0301 1.0073 0.0311
MDA-MB-231 PLX-4720
0.37
uM
LJP5
1.0043 0.0169 1.0026 0.0183
MDA-MB-231 PLX-4720
1.11
uM
LJP5
0.9323 0.0224 0.9286 0.0235
MDA-MB-231 PLX-4720
3.33
uM
LJP5
0.8368 0.0380 0.8221 0.0423
MDA-MB-231 PLX-4720
10
uM
LJP5
0.6793 0.0972 0.6296 0.1216
MDA-MB-231 Lapatinib
0.04
uM
LJP6
0.8854 0.0201 0.8778 0.0189
MDA-MB-231 Lapatinib
0.12
uM
LJP6
0.9418 0.0045 0.9385 0.0045
MDA-MB-231 Lapatinib
0.37
uM
LJP6
0.9568 0.0070 0.9548 0.0060
MDA-MB-231 Lapatinib
1.11
uM
LJP6
0.9518 0.0127 0.9484 0.0147
MDA-MB-231 Lapatinib
3.33
uM
LJP6
0.9499 0.0065 0.9473 0.0066
MDA-MB-231 Lapatinib
10
uM
LJP6
0.6700 0.0417 0.6199 0.0631
MDA-MB-231 Sirolimus
0.04
uM
LJP6
0.8192 0.0232 0.8020 0.0283
MDA-MB-231 Sirolimus
0.12
uM
LJP6
0.8001 0.0217 0.7812 0.0227
MDA-MB-231 Sirolimus
0.37
uM
LJP6
0.8287 0.0212 0.8122 0.0280
MDA-MB-231 Sirolimus
1.11
uM
LJP6
0.8047 0.0243 0.7866 0.0245