LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PIK-93 | 10 | uM | LJP5 | 0.3922 | 0.0277 | 0.0052 | 0.0676 |
| SK-BR-3 | Dactolisib | 0.04 | uM | LJP5 | 0.4347 | 0.0338 | 0.0857 | 0.0374 |
| SK-BR-3 | Dactolisib | 0.12 | uM | LJP5 | 0.4132 | 0.0292 | 0.0449 | 0.0618 |
| SK-BR-3 | Dactolisib | 0.37 | uM | LJP5 | 0.3681 | 0.0337 | -0.0406 | 0.0712 |
| SK-BR-3 | Dactolisib | 1.11 | uM | LJP5 | 0.3682 | 0.0310 | -0.0400 | 0.0647 |
| SK-BR-3 | Dactolisib | 3.33 | uM | LJP5 | 0.3709 | 0.0064 | -0.0350 | 0.0668 |
| SK-BR-3 | Dactolisib | 10 | uM | LJP5 | 0.4058 | 0.0098 | 0.0305 | 0.0661 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 0.9329 | 0.0207 | 0.8960 | 0.0355 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 0.8752 | 0.0180 | 0.8109 | 0.0342 |
| SK-BR-3 | Alpelisib | 0.37 | uM | LJP5 | 0.7878 | 0.0190 | 0.6792 | 0.0294 |
| SK-BR-3 | Alpelisib | 1.11 | uM | LJP5 | 0.7076 | 0.0230 | 0.5534 | 0.0224 |
| SK-BR-3 | Alpelisib | 3.33 | uM | LJP5 | 0.5713 | 0.0197 | 0.3229 | 0.0647 |
| SK-BR-3 | Alpelisib | 10 | uM | LJP5 | 0.3420 | 0.0181 | -0.0922 | 0.0883 |
| SK-BR-3 | GDC-0980 | 0.04 | uM | LJP5 | 0.4984 | 0.0354 | 0.2019 | 0.0302 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 0.3905 | 0.0198 | 0.0037 | 0.0239 |
| SK-BR-3 | GDC-0980 | 0.37 | uM | LJP5 | 0.3637 | 0.0175 | -0.0481 | 0.0472 |
| SK-BR-3 | GDC-0980 | 1.11 | uM | LJP5 | 0.3442 | 0.0127 | -0.0862 | 0.0662 |
| SK-BR-3 | GDC-0980 | 3.33 | uM | LJP5 | 0.3595 | 0.0192 | -0.0566 | 0.0644 |
| SK-BR-3 | GDC-0980 | 10 | uM | LJP5 | 0.3314 | 0.0246 | -0.1114 | 0.0718 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP5 | 0.3732 | 0.0138 | -0.0317 | 0.0790 |
| SK-BR-3 | Mitoxantrone | 0.04 | uM | LJP6 | 0.3627 | 0.0327 | -0.0846 | 0.1290 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP5 | 0.3695 | 0.0285 | -0.0390 | 0.0943 |
| SK-BR-3 | Mitoxantrone | 0.12 | uM | LJP6 | 0.3493 | 0.0402 | -0.1100 | 0.1319 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP5 | 0.3616 | 0.0337 | -0.0545 | 0.1031 |
| SK-BR-3 | Mitoxantrone | 0.37 | uM | LJP6 | 0.3368 | 0.0488 | -0.1350 | 0.1437 |