LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 1.0047 | 0.0062 | 1.0091 | 0.0101 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP5 | 0.9106 | 0.0094 | 0.8653 | 0.0203 |
| SK-BR-3 | PD0325901 | 0.12 | uM | LJP6 | 0.9552 | 0.0249 | 0.9383 | 0.0305 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP5 | 0.9396 | 0.0128 | 0.9077 | 0.0266 |
| SK-BR-3 | PD0325901 | 0.37 | uM | LJP6 | 0.9429 | 0.0287 | 0.9184 | 0.0351 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP5 | 0.8194 | 0.0107 | 0.7201 | 0.0109 |
| SK-BR-3 | PD0325901 | 1.11 | uM | LJP6 | 0.8284 | 0.0290 | 0.7355 | 0.0207 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP5 | 0.6364 | 0.0044 | 0.4216 | 0.0338 |
| SK-BR-3 | PD0325901 | 3.33 | uM | LJP6 | 0.6662 | 0.0302 | 0.4674 | 0.0210 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP5 | 0.4886 | 0.0409 | 0.1650 | 0.1166 |
| SK-BR-3 | PD0325901 | 10 | uM | LJP6 | 0.5300 | 0.0242 | 0.2279 | 0.0477 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 0.4068 | 0.0123 | 0.0313 | 0.0776 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 0.4072 | 0.0075 | 0.0036 | 0.0592 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP5 | 0.3564 | 0.0105 | -0.0642 | 0.0790 |
| SK-BR-3 | Geldanamycin | 0.12 | uM | LJP6 | 0.3685 | 0.0078 | -0.0702 | 0.0604 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP5 | 0.3699 | 0.0104 | -0.0368 | 0.0475 |
| SK-BR-3 | Geldanamycin | 0.37 | uM | LJP6 | 0.3634 | 0.0097 | -0.0799 | 0.0569 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP5 | 0.3805 | 0.0305 | -0.0161 | 0.0267 |
| SK-BR-3 | Geldanamycin | 1.11 | uM | LJP6 | 0.3819 | 0.0205 | -0.0439 | 0.0447 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP5 | 0.2929 | 0.0327 | -0.1912 | 0.0778 |
| SK-BR-3 | Geldanamycin | 3.33 | uM | LJP6 | 0.3109 | 0.0130 | -0.1835 | 0.0605 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP5 | 0.1722 | 0.0206 | -0.4505 | 0.1065 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 0.1937 | 0.0065 | -0.4312 | 0.0608 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 1.0855 | 0.0256 | 1.1190 | 0.0250 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 1.0194 | 0.0215 | 1.0271 | 0.0307 |