LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Crizotinib | 1.11 | uM | LJP5 | 0.7577 | 0.0531 | 0.6288 | 0.0853 |
| SK-BR-3 | Crizotinib | 3.33 | uM | LJP5 | 0.5799 | 0.0550 | 0.3419 | 0.0827 |
| SK-BR-3 | Crizotinib | 10 | uM | LJP5 | 0.2965 | 0.0062 | -0.1806 | 0.0532 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 1.0365 | 0.0170 | 1.0538 | 0.0251 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 1.0074 | 0.0303 | 1.0086 | 0.0508 |
| SK-BR-3 | BMS345541 | 0.37 | uM | LJP6 | 0.9524 | 0.0448 | 0.9288 | 0.0644 |
| SK-BR-3 | BMS345541 | 1.11 | uM | LJP6 | 0.7505 | 0.0160 | 0.6039 | 0.0379 |
| SK-BR-3 | BMS345541 | 3.33 | uM | LJP6 | 0.5113 | 0.0086 | 0.1915 | 0.0762 |
| SK-BR-3 | BMS345541 | 10 | uM | LJP6 | 0.2280 | 0.0500 | -0.3576 | 0.1311 |
| SK-BR-3 | KIN001-043 | 0.04 | uM | LJP6 | 0.9968 | 0.0132 | 0.9921 | 0.0222 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 0.9535 | 0.0060 | 0.9293 | 0.0022 |
| SK-BR-3 | KIN001-043 | 0.37 | uM | LJP6 | 0.8447 | 0.0261 | 0.7629 | 0.0176 |
| SK-BR-3 | KIN001-043 | 1.11 | uM | LJP6 | 0.8029 | 0.0122 | 0.6876 | 0.0394 |
| SK-BR-3 | KIN001-043 | 3.33 | uM | LJP6 | 0.8114 | 0.0177 | 0.6976 | 0.0573 |
| SK-BR-3 | KIN001-043 | 10 | uM | LJP6 | 0.5268 | 0.0279 | 0.2185 | 0.0879 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 1.0952 | 0.0354 | 1.1488 | 0.0565 |
| SK-BR-3 | Saracatinib | 0.12 | uM | LJP6 | 1.0791 | 0.0394 | 1.1155 | 0.0604 |
| SK-BR-3 | Saracatinib | 0.37 | uM | LJP6 | 1.0001 | 0.0249 | 1.0012 | 0.0402 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 0.9505 | 0.0266 | 0.9157 | 0.0462 |
| SK-BR-3 | Saracatinib | 3.33 | uM | LJP6 | 0.8499 | 0.0098 | 0.7629 | 0.0331 |
| SK-BR-3 | Saracatinib | 10 | uM | LJP6 | 0.5188 | 0.0119 | 0.2071 | 0.0660 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 0.7918 | 0.0402 | 0.6751 | 0.0790 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 0.8404 | 0.0141 | 0.7587 | 0.0295 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 0.8446 | 0.0049 | 0.7664 | 0.0118 |
| SK-BR-3 | Sigma A6730 | 1.11 | uM | LJP5 | 0.7320 | 0.0207 | 0.5872 | 0.0526 |