LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MDA-MB-231 | Sirolimus | 3.33 | uM | LJP6 | 0.8043 | 0.0324 | 0.7842 | 0.0407 |
MDA-MB-231 | Sirolimus | 10 | uM | LJP6 | 0.8189 | 0.0388 | 0.7996 | 0.0501 |
MDA-MB-231 | ZSTK474 | 0.04 | uM | LJP6 | 0.8914 | 0.0298 | 0.8815 | 0.0360 |
MDA-MB-231 | ZSTK474 | 0.12 | uM | LJP6 | 0.8431 | 0.0238 | 0.8282 | 0.0317 |
MDA-MB-231 | ZSTK474 | 0.37 | uM | LJP6 | 0.7556 | 0.0061 | 0.7282 | 0.0143 |
MDA-MB-231 | ZSTK474 | 1.11 | uM | LJP6 | 0.6888 | 0.0235 | 0.6464 | 0.0354 |
MDA-MB-231 | ZSTK474 | 3.33 | uM | LJP6 | 0.5851 | 0.0236 | 0.5112 | 0.0443 |
MDA-MB-231 | ZSTK474 | 10 | uM | LJP6 | 0.4967 | 0.0344 | 0.3855 | 0.0658 |
MDA-MB-231 | BX-912 | 0.04 | uM | LJP5 | 0.9090 | 0.0063 | 0.9033 | 0.0057 |
MDA-MB-231 | BX-912 | 0.12 | uM | LJP5 | 0.9083 | 0.0429 | 0.9015 | 0.0479 |
MDA-MB-231 | BX-912 | 0.37 | uM | LJP5 | 0.7412 | 0.1423 | 0.6938 | 0.1835 |
MDA-MB-231 | BX-912 | 1.11 | uM | LJP5 | 0.5114 | 0.0873 | 0.4042 | 0.1333 |
MDA-MB-231 | BX-912 | 3.33 | uM | LJP5 | 0.3697 | 0.0420 | 0.1939 | 0.0779 |
MDA-MB-231 | BX-912 | 10 | uM | LJP5 | 0.2595 | 0.0751 | -0.0228 | 0.1548 |
MDA-MB-231 | Selumetinib | 0.04 | uM | LJP6 | 0.8588 | 0.0389 | 0.8461 | 0.0450 |
MDA-MB-231 | Selumetinib | 0.12 | uM | LJP6 | 0.7329 | 0.0491 | 0.7016 | 0.0558 |
MDA-MB-231 | Selumetinib | 0.37 | uM | LJP6 | 0.6090 | 0.0460 | 0.5454 | 0.0508 |
MDA-MB-231 | Selumetinib | 1.11 | uM | LJP6 | 0.5445 | 0.0354 | 0.4580 | 0.0392 |
MDA-MB-231 | Selumetinib | 3.33 | uM | LJP6 | 0.4764 | 0.0292 | 0.3596 | 0.0389 |
MDA-MB-231 | Selumetinib | 10 | uM | LJP6 | 0.3753 | 0.0187 | 0.1998 | 0.0476 |
MDA-MB-231 | MK2206 | 0.04 | uM | LJP6 | 0.9703 | 0.0204 | 0.9678 | 0.0227 |
MDA-MB-231 | MK2206 | 0.12 | uM | LJP6 | 0.9090 | 0.0226 | 0.9037 | 0.0227 |
MDA-MB-231 | MK2206 | 0.37 | uM | LJP6 | 0.8343 | 0.0303 | 0.8214 | 0.0289 |
MDA-MB-231 | MK2206 | 1.11 | uM | LJP6 | 0.8208 | 0.0351 | 0.8056 | 0.0352 |
MDA-MB-231 | MK2206 | 3.33 | uM | LJP6 | 0.7794 | 0.0292 | 0.7569 | 0.0297 |