LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
MDA-MB-231 Sirolimus
3.33
uM
LJP6
0.8043 0.0324 0.7842 0.0407
MDA-MB-231 Sirolimus
10
uM
LJP6
0.8189 0.0388 0.7996 0.0501
MDA-MB-231 ZSTK474
0.04
uM
LJP6
0.8914 0.0298 0.8815 0.0360
MDA-MB-231 ZSTK474
0.12
uM
LJP6
0.8431 0.0238 0.8282 0.0317
MDA-MB-231 ZSTK474
0.37
uM
LJP6
0.7556 0.0061 0.7282 0.0143
MDA-MB-231 ZSTK474
1.11
uM
LJP6
0.6888 0.0235 0.6464 0.0354
MDA-MB-231 ZSTK474
3.33
uM
LJP6
0.5851 0.0236 0.5112 0.0443
MDA-MB-231 ZSTK474
10
uM
LJP6
0.4967 0.0344 0.3855 0.0658
MDA-MB-231 BX-912
0.04
uM
LJP5
0.9090 0.0063 0.9033 0.0057
MDA-MB-231 BX-912
0.12
uM
LJP5
0.9083 0.0429 0.9015 0.0479
MDA-MB-231 BX-912
0.37
uM
LJP5
0.7412 0.1423 0.6938 0.1835
MDA-MB-231 BX-912
1.11
uM
LJP5
0.5114 0.0873 0.4042 0.1333
MDA-MB-231 BX-912
3.33
uM
LJP5
0.3697 0.0420 0.1939 0.0779
MDA-MB-231 BX-912
10
uM
LJP5
0.2595 0.0751 -0.0228 0.1548
MDA-MB-231 Selumetinib
0.04
uM
LJP6
0.8588 0.0389 0.8461 0.0450
MDA-MB-231 Selumetinib
0.12
uM
LJP6
0.7329 0.0491 0.7016 0.0558
MDA-MB-231 Selumetinib
0.37
uM
LJP6
0.6090 0.0460 0.5454 0.0508
MDA-MB-231 Selumetinib
1.11
uM
LJP6
0.5445 0.0354 0.4580 0.0392
MDA-MB-231 Selumetinib
3.33
uM
LJP6
0.4764 0.0292 0.3596 0.0389
MDA-MB-231 Selumetinib
10
uM
LJP6
0.3753 0.0187 0.1998 0.0476
MDA-MB-231 MK2206
0.04
uM
LJP6
0.9703 0.0204 0.9678 0.0227
MDA-MB-231 MK2206
0.12
uM
LJP6
0.9090 0.0226 0.9037 0.0227
MDA-MB-231 MK2206
0.37
uM
LJP6
0.8343 0.0303 0.8214 0.0289
MDA-MB-231 MK2206
1.11
uM
LJP6
0.8208 0.0351 0.8056 0.0352
MDA-MB-231 MK2206
3.33
uM
LJP6
0.7794 0.0292 0.7569 0.0297