LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP5 | 0.1430 | 0.0309 | -0.2733 | 0.0908 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 0.1302 | 0.0284 | -0.3163 | 0.1029 |
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP5 | 0.1436 | 0.0258 | -0.2687 | 0.0767 |
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP6 | 0.1123 | 0.0244 | -0.3681 | 0.0980 |
| MDA-MB-231 | CGP60474 | 10 | uM | LJP5 | 0.1425 | 0.0230 | -0.2704 | 0.0706 |
| MDA-MB-231 | CGP60474 | 10 | uM | LJP6 | 0.1116 | 0.0176 | -0.3684 | 0.0764 |
| MDA-MB-231 | PD173074 | 0.04 | uM | LJP6 | 1.0822 | 0.0338 | 1.0818 | 0.0305 |
| MDA-MB-231 | PD173074 | 0.12 | uM | LJP6 | 1.0677 | 0.0199 | 1.0684 | 0.0187 |
| MDA-MB-231 | PD173074 | 0.37 | uM | LJP6 | 1.0728 | 0.0429 | 1.0765 | 0.0456 |
| MDA-MB-231 | PD173074 | 1.11 | uM | LJP6 | 1.0646 | 0.0283 | 1.0669 | 0.0314 |
| MDA-MB-231 | PD173074 | 3.33 | uM | LJP6 | 1.0427 | 0.0086 | 1.0447 | 0.0102 |
| MDA-MB-231 | PD173074 | 10 | uM | LJP6 | 0.2992 | 0.0639 | 0.0514 | 0.1308 |
| MDA-MB-231 | Crizotinib | 0.04 | uM | LJP5 | 0.8438 | 0.0690 | 0.8308 | 0.0762 |
| MDA-MB-231 | Crizotinib | 0.12 | uM | LJP5 | 0.8915 | 0.0425 | 0.8854 | 0.0455 |
| MDA-MB-231 | Crizotinib | 0.37 | uM | LJP5 | 0.7964 | 0.0491 | 0.7784 | 0.0552 |
| MDA-MB-231 | Crizotinib | 1.11 | uM | LJP5 | 0.5848 | 0.0874 | 0.5093 | 0.1152 |
| MDA-MB-231 | Crizotinib | 3.33 | uM | LJP5 | 0.3575 | 0.0392 | 0.1751 | 0.0679 |
| MDA-MB-231 | Crizotinib | 10 | uM | LJP5 | 0.2553 | 0.0342 | -0.0131 | 0.0738 |
| MDA-MB-231 | BMS345541 | 0.04 | uM | LJP6 | 0.9935 | 0.0052 | 0.9929 | 0.0056 |
| MDA-MB-231 | BMS345541 | 0.12 | uM | LJP6 | 0.9452 | 0.0504 | 0.9364 | 0.0558 |
| MDA-MB-231 | BMS345541 | 0.37 | uM | LJP6 | 0.8940 | 0.0284 | 0.8850 | 0.0347 |
| MDA-MB-231 | BMS345541 | 1.11 | uM | LJP6 | 0.6941 | 0.0380 | 0.6523 | 0.0492 |
| MDA-MB-231 | BMS345541 | 3.33 | uM | LJP6 | 0.4162 | 0.0470 | 0.2648 | 0.0651 |
| MDA-MB-231 | BMS345541 | 10 | uM | LJP6 | 0.1545 | 0.0348 | -0.2530 | 0.1127 |
| MDA-MB-231 | KIN001-043 | 0.04 | uM | LJP6 | 0.9270 | 0.0347 | 0.9198 | 0.0409 |