LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MDA-MB-231 | KIN001-043 | 0.12 | uM | LJP6 | 0.8558 | 0.0366 | 0.8403 | 0.0457 |
MDA-MB-231 | KIN001-043 | 0.37 | uM | LJP6 | 0.8353 | 0.0127 | 0.8195 | 0.0191 |
MDA-MB-231 | KIN001-043 | 1.11 | uM | LJP6 | 0.8339 | 0.0401 | 0.8159 | 0.0512 |
MDA-MB-231 | KIN001-043 | 3.33 | uM | LJP6 | 0.8702 | 0.0555 | 0.8552 | 0.0674 |
MDA-MB-231 | KIN001-043 | 10 | uM | LJP6 | 0.4039 | 0.0752 | 0.2315 | 0.1429 |
MDA-MB-231 | Saracatinib | 0.04 | uM | LJP6 | 0.8747 | 0.0360 | 0.8625 | 0.0435 |
MDA-MB-231 | Saracatinib | 0.12 | uM | LJP6 | 0.7382 | 0.0382 | 0.7044 | 0.0498 |
MDA-MB-231 | Saracatinib | 0.37 | uM | LJP6 | 0.6423 | 0.0264 | 0.5869 | 0.0376 |
MDA-MB-231 | Saracatinib | 1.11 | uM | LJP6 | 0.5836 | 0.0388 | 0.5101 | 0.0518 |
MDA-MB-231 | Saracatinib | 3.33 | uM | LJP6 | 0.5699 | 0.0446 | 0.4887 | 0.0665 |
MDA-MB-231 | Saracatinib | 10 | uM | LJP6 | 0.4709 | 0.0366 | 0.3477 | 0.0644 |
MDA-MB-231 | Sigma A6730 | 0.04 | uM | LJP5 | 0.8821 | 0.0484 | 0.8740 | 0.0525 |
MDA-MB-231 | Sigma A6730 | 0.12 | uM | LJP5 | 0.8950 | 0.0463 | 0.8888 | 0.0499 |
MDA-MB-231 | Sigma A6730 | 0.37 | uM | LJP5 | 0.9214 | 0.0256 | 0.9178 | 0.0268 |
MDA-MB-231 | Sigma A6730 | 1.11 | uM | LJP5 | 0.8461 | 0.0439 | 0.8351 | 0.0481 |
MDA-MB-231 | Sigma A6730 | 3.33 | uM | LJP5 | 0.8933 | 0.0131 | 0.8876 | 0.0134 |
MDA-MB-231 | Sigma A6730 | 10 | uM | LJP5 | 0.6190 | 0.0486 | 0.5600 | 0.0623 |
MDA-MB-231 | WH-4-025 | 0.04 | uM | LJP5 | 0.8336 | 0.0163 | 0.8203 | 0.0191 |
MDA-MB-231 | WH-4-025 | 0.12 | uM | LJP5 | 0.6092 | 0.0691 | 0.5448 | 0.0886 |
MDA-MB-231 | WH-4-025 | 0.37 | uM | LJP5 | 0.4062 | 0.0775 | 0.2462 | 0.1278 |
MDA-MB-231 | WH-4-025 | 1.11 | uM | LJP5 | 0.2408 | 0.0377 | -0.0445 | 0.0797 |
MDA-MB-231 | WH-4-025 | 3.33 | uM | LJP5 | 0.2403 | 0.0302 | -0.0430 | 0.0667 |
MDA-MB-231 | WH-4-025 | 10 | uM | LJP5 | 0.1726 | 0.0413 | -0.2033 | 0.1145 |
MDA-MB-231 | R406 | 0.04 | uM | LJP6 | 0.9930 | 0.0139 | 0.9929 | 0.0139 |
MDA-MB-231 | R406 | 0.12 | uM | LJP6 | 0.9590 | 0.0293 | 0.9581 | 0.0292 |