LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Gefitinib | 3.33 | uM | LJP6 | 1.0114 | 0.0392 | 1.0087 | 0.0396 |
| MDA-MB-231 | Gefitinib | 10 | uM | LJP6 | 0.9028 | 0.0119 | 0.8965 | 0.0122 |
| MDA-MB-231 | Nilotinib | 0.04 | uM | LJP5 | 0.9466 | 0.0212 | 0.9433 | 0.0221 |
| MDA-MB-231 | Nilotinib | 0.12 | uM | LJP5 | 0.9199 | 0.0539 | 0.9138 | 0.0574 |
| MDA-MB-231 | Nilotinib | 0.37 | uM | LJP5 | 0.8732 | 0.0534 | 0.8631 | 0.0583 |
| MDA-MB-231 | Nilotinib | 1.11 | uM | LJP5 | 0.8229 | 0.0734 | 0.8047 | 0.0835 |
| MDA-MB-231 | Nilotinib | 3.33 | uM | LJP5 | 0.8331 | 0.0687 | 0.8177 | 0.0774 |
| MDA-MB-231 | Nilotinib | 10 | uM | LJP5 | 0.2687 | 0.0467 | 0.0100 | 0.0929 |
| MDA-MB-231 | JNK-9L | 0.04 | uM | LJP6 | 0.8190 | 0.0426 | 0.8039 | 0.0429 |
| MDA-MB-231 | JNK-9L | 0.12 | uM | LJP6 | 0.7547 | 0.0314 | 0.7281 | 0.0294 |
| MDA-MB-231 | JNK-9L | 0.37 | uM | LJP6 | 0.5583 | 0.0225 | 0.4748 | 0.0405 |
| MDA-MB-231 | JNK-9L | 1.11 | uM | LJP6 | 0.2928 | 0.0485 | 0.0463 | 0.1134 |
| MDA-MB-231 | JNK-9L | 3.33 | uM | LJP6 | 0.2061 | 0.0255 | -0.1242 | 0.0784 |
| MDA-MB-231 | JNK-9L | 10 | uM | LJP6 | 0.1837 | 0.0324 | -0.1784 | 0.0993 |
| MDA-MB-231 | PD0325901 | 0.04 | uM | LJP5 | 0.6623 | 0.0301 | 0.6182 | 0.0347 |
| MDA-MB-231 | PD0325901 | 0.04 | uM | LJP6 | 0.6451 | 0.0169 | 0.5919 | 0.0113 |
| MDA-MB-231 | PD0325901 | 0.12 | uM | LJP5 | 0.5126 | 0.0092 | 0.4184 | 0.0095 |
| MDA-MB-231 | PD0325901 | 0.12 | uM | LJP6 | 0.5086 | 0.0217 | 0.4071 | 0.0239 |
| MDA-MB-231 | PD0325901 | 0.37 | uM | LJP5 | 0.4192 | 0.0115 | 0.2783 | 0.0232 |
| MDA-MB-231 | PD0325901 | 0.37 | uM | LJP6 | 0.4052 | 0.0085 | 0.2500 | 0.0122 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP5 | 0.3255 | 0.0250 | 0.1207 | 0.0509 |
| MDA-MB-231 | PD0325901 | 1.11 | uM | LJP6 | 0.2844 | 0.0242 | 0.0351 | 0.0619 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP5 | 0.2639 | 0.0216 | 0.0055 | 0.0484 |
| MDA-MB-231 | PD0325901 | 3.33 | uM | LJP6 | 0.2220 | 0.0288 | -0.0950 | 0.0853 |
| MDA-MB-231 | PD0325901 | 10 | uM | LJP5 | 0.2301 | 0.0261 | -0.0647 | 0.0638 |