LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 0.9634 | 0.0125 | 0.9469 | 0.0162 |
| SK-BR-3 | Nintedanib | 1.11 | uM | LJP6 | 0.8916 | 0.0156 | 0.8352 | 0.0127 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 0.7745 | 0.0344 | 0.6450 | 0.0550 |
| SK-BR-3 | Nintedanib | 10 | uM | LJP6 | 0.4313 | 0.1366 | 0.0487 | 0.2115 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 1.0531 | 0.0197 | 1.0730 | 0.0217 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 0.8839 | 0.0999 | 0.8119 | 0.1505 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 0.4303 | 0.0197 | 0.0769 | 0.0400 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 0.3594 | 0.0090 | -0.0562 | 0.0457 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 0.3710 | 0.0108 | -0.0340 | 0.0480 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 0.3387 | 0.0143 | -0.0967 | 0.0621 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 0.9284 | 0.0177 | 0.8908 | 0.0206 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 0.7637 | 0.0206 | 0.6276 | 0.0073 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 0.5662 | 0.0201 | 0.2918 | 0.0495 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 0.3345 | 0.0260 | -0.1371 | 0.0669 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 0.2636 | 0.0173 | -0.2795 | 0.0890 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 0.1822 | 0.0251 | -0.4527 | 0.1156 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 0.7417 | 0.0966 | 0.6183 | 0.1223 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 0.5703 | 0.0993 | 0.3317 | 0.1239 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 0.3428 | 0.0284 | -0.0907 | 0.1020 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 0.3406 | 0.0303 | -0.0946 | 0.0983 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 0.3630 | 0.0352 | -0.0520 | 0.0926 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 0.2737 | 0.0088 | -0.2272 | 0.0554 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 0.3960 | 0.0171 | 0.0117 | 0.0746 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 0.3969 | 0.0205 | 0.0142 | 0.0667 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 0.4040 | 0.0276 | 0.0266 | 0.0739 |