LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Dasatinib | 10 | uM | LJP6 | 0.1212 | 0.0118 | -0.3369 | 0.0542 |
| MDA-MB-231 | Tozasertib | 0.04 | uM | LJP5 | 0.3000 | 0.0047 | 0.0769 | 0.0132 |
| MDA-MB-231 | Tozasertib | 0.12 | uM | LJP5 | 0.2892 | 0.0119 | 0.0560 | 0.0258 |
| MDA-MB-231 | Tozasertib | 0.37 | uM | LJP5 | 0.3083 | 0.0104 | 0.0918 | 0.0212 |
| MDA-MB-231 | Tozasertib | 1.11 | uM | LJP5 | 0.2970 | 0.0100 | 0.0708 | 0.0225 |
| MDA-MB-231 | Tozasertib | 3.33 | uM | LJP5 | 0.3118 | 0.0100 | 0.0979 | 0.0222 |
| MDA-MB-231 | Tozasertib | 10 | uM | LJP5 | 0.3153 | 0.0404 | 0.1002 | 0.0757 |
| MDA-MB-231 | Imatinib | 0.04 | uM | LJP6 | 1.0141 | 0.0321 | 1.0122 | 0.0317 |
| MDA-MB-231 | Imatinib | 0.12 | uM | LJP6 | 1.0005 | 0.0183 | 0.9993 | 0.0186 |
| MDA-MB-231 | Imatinib | 0.37 | uM | LJP6 | 1.0162 | 0.0233 | 1.0153 | 0.0228 |
| MDA-MB-231 | Imatinib | 1.11 | uM | LJP6 | 1.0029 | 0.0264 | 1.0008 | 0.0263 |
| MDA-MB-231 | Imatinib | 3.33 | uM | LJP6 | 1.0158 | 0.0161 | 1.0152 | 0.0161 |
| MDA-MB-231 | Imatinib | 10 | uM | LJP6 | 0.9197 | 0.0129 | 0.9153 | 0.0126 |
| MDA-MB-231 | NVP-TAE684 | 0.04 | uM | LJP6 | 0.9138 | 0.0172 | 0.9079 | 0.0205 |
| MDA-MB-231 | NVP-TAE684 | 0.12 | uM | LJP6 | 0.7626 | 0.0572 | 0.7372 | 0.0613 |
| MDA-MB-231 | NVP-TAE684 | 0.37 | uM | LJP6 | 0.7284 | 0.0378 | 0.6940 | 0.0512 |
| MDA-MB-231 | NVP-TAE684 | 1.11 | uM | LJP6 | 0.4999 | 0.0474 | 0.3888 | 0.0808 |
| MDA-MB-231 | NVP-TAE684 | 3.33 | uM | LJP6 | 0.3291 | 0.0350 | 0.1174 | 0.0784 |
| MDA-MB-231 | NVP-TAE684 | 10 | uM | LJP6 | 0.1656 | 0.0395 | -0.2282 | 0.1224 |
| MDA-MB-231 | CGP60474 | 0.04 | uM | LJP5 | 0.7235 | 0.0175 | 0.6929 | 0.0214 |
| MDA-MB-231 | CGP60474 | 0.04 | uM | LJP6 | 0.1845 | 0.0358 | -0.1783 | 0.1073 |
| MDA-MB-231 | CGP60474 | 0.12 | uM | LJP5 | 0.2312 | 0.0338 | -0.0639 | 0.0803 |
| MDA-MB-231 | CGP60474 | 0.12 | uM | LJP6 | 0.1694 | 0.0345 | -0.2139 | 0.1055 |
| MDA-MB-231 | CGP60474 | 0.37 | uM | LJP5 | 0.1599 | 0.0267 | -0.2264 | 0.0748 |
| MDA-MB-231 | CGP60474 | 0.37 | uM | LJP6 | 0.1654 | 0.0356 | -0.2250 | 0.1107 |