LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | HG-6-64-01 | 3.33 | uM | LJP6 | 0.3025 | 0.0453 | 0.0606 | 0.0983 |
| MDA-MB-231 | HG-6-64-01 | 10 | uM | LJP6 | 0.1225 | 0.0355 | -0.3499 | 0.1306 |
| MDA-MB-231 | Neratinib | 0.04 | uM | LJP5 | 0.9134 | 0.0691 | 0.9072 | 0.0749 |
| MDA-MB-231 | Neratinib | 0.12 | uM | LJP5 | 0.8786 | 0.0799 | 0.8685 | 0.0884 |
| MDA-MB-231 | Neratinib | 0.37 | uM | LJP5 | 0.7541 | 0.0620 | 0.7275 | 0.0721 |
| MDA-MB-231 | Neratinib | 1.11 | uM | LJP5 | 0.6417 | 0.1038 | 0.5805 | 0.1304 |
| MDA-MB-231 | Neratinib | 3.33 | uM | LJP5 | 0.5042 | 0.1155 | 0.3867 | 0.1665 |
| MDA-MB-231 | Neratinib | 10 | uM | LJP5 | 0.3208 | 0.1296 | 0.0691 | 0.2239 |
| MDA-MB-231 | JW-7-24-1 | 0.04 | uM | LJP6 | 0.8369 | 0.0648 | 0.8231 | 0.0687 |
| MDA-MB-231 | JW-7-24-1 | 0.12 | uM | LJP6 | 0.8681 | 0.0496 | 0.8587 | 0.0508 |
| MDA-MB-231 | JW-7-24-1 | 0.37 | uM | LJP6 | 0.7775 | 0.0494 | 0.7542 | 0.0518 |
| MDA-MB-231 | JW-7-24-1 | 1.11 | uM | LJP6 | 0.6717 | 0.0573 | 0.6237 | 0.0669 |
| MDA-MB-231 | JW-7-24-1 | 3.33 | uM | LJP6 | 0.6090 | 0.0511 | 0.5434 | 0.0617 |
| MDA-MB-231 | JW-7-24-1 | 10 | uM | LJP6 | 0.2090 | 0.0332 | -0.1216 | 0.0962 |
| MDA-MB-231 | Dasatinib | 0.04 | uM | LJP5 | 0.5098 | 0.0346 | 0.4132 | 0.0455 |
| MDA-MB-231 | Dasatinib | 0.04 | uM | LJP6 | 0.2187 | 0.0206 | -0.0952 | 0.0570 |
| MDA-MB-231 | Dasatinib | 0.12 | uM | LJP5 | 0.2489 | 0.0214 | -0.0230 | 0.0367 |
| MDA-MB-231 | Dasatinib | 0.12 | uM | LJP6 | 0.1760 | 0.0061 | -0.1903 | 0.0102 |
| MDA-MB-231 | Dasatinib | 0.37 | uM | LJP5 | 0.1659 | 0.0108 | -0.2066 | 0.0243 |
| MDA-MB-231 | Dasatinib | 0.37 | uM | LJP6 | 0.1715 | 0.0095 | -0.2012 | 0.0161 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP5 | 0.1577 | 0.0149 | -0.2279 | 0.0395 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP6 | 0.1569 | 0.0107 | -0.2385 | 0.0298 |
| MDA-MB-231 | Dasatinib | 3.33 | uM | LJP5 | 0.1611 | 0.0138 | -0.2186 | 0.0367 |
| MDA-MB-231 | Dasatinib | 3.33 | uM | LJP6 | 0.1495 | 0.0144 | -0.2587 | 0.0363 |
| MDA-MB-231 | Dasatinib | 10 | uM | LJP5 | 0.1782 | 0.0224 | -0.1803 | 0.0605 |