LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
10
uM
LJP6
 72
hr
 1235 1856 4405 0.4218 0.2441
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 72
hr
 1235 4318 4660 0.9267 0.9220
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 72
hr
 1235 4131 4660 0.8862 0.8769
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 1235 3974 4660 0.8533 0.8412
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 72
hr
 1235 3777 4660 0.8101 0.7911
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 1235 3381 4660 0.7251 0.6898
MDA-MB-231 AZD-6482
10
uM
LJP5
 72
hr
 1235 3063 4660 0.6573 0.6058
MDA-MB-231 NU7441
0.04
uM
LJP5
 72
hr
 1235 4817 4660 1.0351 1.0372
MDA-MB-231 NU7441
0.12
uM
LJP5
 72
hr
 1235 4631 4660 0.9979 0.9983
MDA-MB-231 NU7441
0.37
uM
LJP5
 72
hr
 1235 4558 4660 0.9797 0.9796
MDA-MB-231 NU7441
1.11
uM
LJP5
 72
hr
 1235 4212 4660 0.9055 0.8997
MDA-MB-231 NU7441
3.33
uM
LJP5
 72
hr
 1235 2712 4660 0.5852 0.5096
MDA-MB-231 NU7441
10
uM
LJP5
 72
hr
 1235 1195 4660 0.2572 -0.0169
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 1235 4518 4405 1.0262 1.0286
MDA-MB-231 OSI-027
0.12
uM
LJP6
 72
hr
 1235 4078 4405 0.9253 0.9142
MDA-MB-231 OSI-027
0.37
uM
LJP6
 72
hr
 1235 3706 4405 0.8424 0.8201
MDA-MB-231 OSI-027
1.11
uM
LJP6
 72
hr
 1235 3459 4405 0.7867 0.7548
MDA-MB-231 OSI-027
3.33
uM
LJP6
 72
hr
 1235 2665 4405 0.6061 0.5215
MDA-MB-231 OSI-027
10
uM
LJP6
 72
hr
 1235 1591 4405 0.3611 0.1466
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 1235 2048 4405 0.4644 0.3153
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 72
hr
 1235 1684 4405 0.3823 0.1832
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 72
hr
 1235 1597 4405 0.3626 0.1497
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 72
hr
 1235 1697 4405 0.3855 0.1889
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 72
hr
 1235 1552 4405 0.3526 0.1324
MDA-MB-231 WYE-125132
10
uM
LJP6
 72
hr
 1235 1212 4405 0.2753 -0.0108