LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1209 | 4445 | 4203 | 1.0582 | 1.0640 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 4189 | 4203 | 0.9983 | 0.9990 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 3931 | 4203 | 0.9357 | 0.9273 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 3350 | 4203 | 0.7974 | 0.7628 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 3016 | 4203 | 0.7184 | 0.6637 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 72 | hr | 1209 | 1223 | 4203 | 0.2908 | 0.0047 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1716 | 4012 | 0.4263 | 0.2189 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 653 | 4012 | 0.1621 | -0.3030 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 604 | 4012 | 0.1507 | -0.3309 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 591 | 4012 | 0.1472 | -0.3407 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 502 | 4012 | 0.1251 | -0.3993 |
| MCF7 | AT-7519 | 10 | uM | LJP6 | 72 | hr | 1209 | 443 | 4012 | 0.1106 | -0.4408 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1961 | 4012 | 0.4890 | 0.3221 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1692 | 4012 | 0.4224 | 0.2147 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1453 | 4012 | 0.3622 | 0.1113 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1184 | 4012 | 0.2951 | -0.0132 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 993 | 4012 | 0.2477 | -0.1080 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 72 | hr | 1209 | 617 | 4012 | 0.1545 | -0.3225 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1199 | 4012 | 0.2986 | -0.0063 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1108 | 4012 | 0.2765 | -0.0494 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1030 | 4012 | 0.2570 | -0.0888 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1024 | 4012 | 0.2558 | -0.0924 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 985 | 4012 | 0.2457 | -0.1122 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 72 | hr | 1209 | 388 | 4012 | 0.0968 | -0.4820 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1209 | 3745 | 4012 | 0.9334 | 0.9219 |