LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 1235 2739 4405 0.6225 0.5442
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2749 4405 0.6241 0.5463
MDA-MB-231 Afatinib
10
uM
LJP6
 72
hr
 1235 628 4405 0.1427 -0.3090
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 72
hr
 1235 3957 4405 0.8986 0.8867
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 72
hr
 1235 3949 4405 0.8970 0.8852
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 72
hr
 1235 4087 4405 0.9285 0.9211
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 72
hr
 1235 3966 4405 0.9004 0.8888
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 72
hr
 1235 4370 4405 0.9931 0.9929
MDA-MB-231 GSK1904529A
10
uM
LJP6
 72
hr
 1235 4220 4405 0.9590 0.9553
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 72
hr
 1235 3774 4660 0.8103 0.7915
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 72
hr
 1235 3882 4660 0.8329 0.8174
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 72
hr
 1235 3787 4660 0.8120 0.7932
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 72
hr
 1235 3795 4660 0.8132 0.7939
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 72
hr
 1235 3795 4660 0.8131 0.7934
MDA-MB-231 Linsitinib
10
uM
LJP5
 72
hr
 1235 3356 4660 0.7197 0.6833
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1235 4156 4660 0.8910 0.8822
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1235 4191 4660 0.8968 0.8866
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1235 4096 4660 0.8758 0.8621
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1235 4119 4660 0.8828 0.8727
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1235 4242 4660 0.9088 0.9010
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 72
hr
 1235 2267 4660 0.4859 0.3702
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 72
hr
 1235 4092 4660 0.8770 0.8662
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 72
hr
 1235 3565 4660 0.7629 0.7330
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 72
hr
 1235 2970 4660 0.6362 0.5777
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 72
hr
 1235 2108 4660 0.4514 0.3181