LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PI103
0.37
uM
LJP6
 72
hr
 1235 1617 4405 0.3721 0.1286
MDA-MB-231 PI103
1.11
uM
LJP6
 72
hr
 1235 1835 4405 0.4173 0.2406
MDA-MB-231 PI103
3.33
uM
LJP6
 72
hr
 1235 1612 4405 0.3664 0.1556
MDA-MB-231 PI103
10
uM
LJP6
 72
hr
 1235 1139 4405 0.2586 -0.0442
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 72
hr
 1235 4560 4660 0.9773 0.9749
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 72
hr
 1235 3912 4660 0.8390 0.8241
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 72
hr
 1235 2602 4660 0.5562 0.4684
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 72
hr
 1235 2184 4660 0.4681 0.3439
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 72
hr
 1235 1938 4660 0.4162 0.2647
MDA-MB-231 Dovitinib
10
uM
LJP5
 72
hr
 1235 1548 4660 0.3319 0.1233
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 72
hr
 1235 4161 4660 0.8914 0.8820
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 72
hr
 1235 4227 4660 0.9062 0.8987
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 72
hr
 1235 4346 4660 0.9315 0.9261
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 72
hr
 1235 4524 4660 0.9696 0.9668
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 72
hr
 1235 4823 4660 1.0351 1.0365
MDA-MB-231 GSK 690693
10
uM
LJP5
 72
hr
 1235 3718 4660 0.7978 0.7771
MDA-MB-231 SNS-032
0.04
uM
LJP6
 72
hr
 1235 2289 4405 0.5185 0.3954
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 1235 554 4405 0.1259 -0.3546
MDA-MB-231 SNS-032
0.37
uM
LJP6
 72
hr
 1235 489 4405 0.1109 -0.3977
MDA-MB-231 SNS-032
1.11
uM
LJP6
 72
hr
 1235 525 4405 0.1194 -0.3735
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 1235 530 4405 0.1203 -0.3708
MDA-MB-231 SNS-032
10
uM
LJP6
 72
hr
 1235 590 4405 0.1340 -0.3322
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1235 4254 4405 0.9654 0.9608
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 1235 4078 4405 0.9259 0.9175
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3577 4405 0.8130 0.7868