LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Barasertib
0.04
uM
LJP5
 72
hr
 1235 1520 4660 0.3265 0.1139
MDA-MB-231 Barasertib
0.12
uM
LJP5
 72
hr
 1235 1523 4660 0.3277 0.1159
MDA-MB-231 Barasertib
0.37
uM
LJP5
 72
hr
 1235 1541 4660 0.3327 0.1231
MDA-MB-231 Barasertib
1.11
uM
LJP5
 72
hr
 1235 1451 4660 0.3114 0.0866
MDA-MB-231 Barasertib
3.33
uM
LJP5
 72
hr
 1235 1444 4660 0.3109 0.0853
MDA-MB-231 Barasertib
10
uM
LJP5
 72
hr
 1235 1397 4660 0.3003 0.0663
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4745 4660 1.0211 1.0230
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 72
hr
 1235 4648 4660 0.9988 0.9996
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 72
hr
 1235 4614 4660 0.9922 0.9928
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 72
hr
 1235 4371 4660 0.9393 0.9359
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 72
hr
 1235 4224 4660 0.9066 0.9002
MDA-MB-231 Vemurafenib
10
uM
LJP5
 72
hr
 1235 2280 4660 0.4894 0.3762
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 72
hr
 1235 4685 4660 1.0065 1.0073
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 72
hr
 1235 4878 4660 1.0475 1.0495
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4829 4660 1.0378 1.0399
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 72
hr
 1235 4883 4660 1.0496 1.0523
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 72
hr
 1235 4809 4660 1.0325 1.0341
MDA-MB-231 Enzastaurin
10
uM
LJP5
 72
hr
 1235 5177 4660 1.1109 1.1130
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 72
hr
 1235 2837 4405 0.6438 0.5726
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 72
hr
 1235 2570 4405 0.5834 0.4902
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 72
hr
 1235 2272 4405 0.5162 0.3939
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 72
hr
 1235 2231 4405 0.5062 0.3788
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 72
hr
 1235 2077 4405 0.4721 0.3271
MDA-MB-231 Palbociclib
10
uM
LJP6
 72
hr
 1235 1812 4405 0.4124 0.2330
MDA-MB-231 PF562271
0.04
uM
LJP6
 72
hr
 1235 3875 4405 0.8803 0.8659