LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PF562271
0.12
uM
LJP6
 72
hr
 1235 3386 4405 0.7683 0.7315
MDA-MB-231 PF562271
0.37
uM
LJP6
 72
hr
 1235 3116 4405 0.7068 0.6541
MDA-MB-231 PF562271
1.11
uM
LJP6
 72
hr
 1235 2354 4405 0.5345 0.4208
MDA-MB-231 PF562271
3.33
uM
LJP6
 72
hr
 1235 1258 4405 0.2850 0.0072
MDA-MB-231 PF562271
10
uM
LJP6
 72
hr
 1235 460 4405 0.1045 -0.4169
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 72
hr
 1235 2392 4405 0.5431 0.4333
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 72
hr
 1235 1698 4405 0.3855 0.1887
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 72
hr
 1235 1167 4405 0.2649 -0.0315
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 72
hr
 1235 924 4405 0.2094 -0.1486
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 72
hr
 1235 690 4405 0.1567 -0.2726
MDA-MB-231 PHA-793887
10
uM
LJP6
 72
hr
 1235 398 4405 0.0905 -0.4615
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 72
hr
 1235 4105 4405 0.9329 0.9261
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 72
hr
 1235 3854 4405 0.8755 0.8602
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 72
hr
 1235 3389 4405 0.7695 0.7335
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 72
hr
 1235 2766 4405 0.6279 0.5514
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 72
hr
 1235 2125 4405 0.4828 0.3442
MDA-MB-231 QL-X-138
10
uM
LJP6
 72
hr
 1235 760 4405 0.1723 -0.2345
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 72
hr
 1235 2742 4405 0.6230 0.5450
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 72
hr
 1235 2314 4405 0.5247 0.4058
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 72
hr
 1235 1785 4405 0.4047 0.2201
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 72
hr
 1235 1211 4405 0.2752 -0.0111
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 72
hr
 1235 997 4405 0.2266 -0.1107
MDA-MB-231 QL-XII-47
10
uM
LJP6
 72
hr
 1235 717 4405 0.1634 -0.2569
MDA-MB-231 Torin1
0.04
uM
LJP6
 72
hr
 1235 2359 4405 0.5361 0.4229
MDA-MB-231 Torin1
0.12
uM
LJP6
 72
hr
 1235 1985 4405 0.4515 0.2944