LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 1235 436 4405 0.0982 -0.4446
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 72
hr
 1235 1382 4660 0.2969 0.0601
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 1235 1317 4660 0.2835 0.0342
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 1235 1444 4660 0.3105 0.0848
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 1235 1351 4660 0.2908 0.0481
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 72
hr
 1235 1421 4660 0.3060 0.0759
MDA-MB-231 Tozasertib
10
uM
LJP5
 72
hr
 1235 1261 4660 0.2707 0.0097
MDA-MB-231 Imatinib
0.04
uM
LJP6
 72
hr
 1235 4316 4405 0.9807 0.9791
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 1235 4326 4405 0.9829 0.9817
MDA-MB-231 Imatinib
0.37
uM
LJP6
 72
hr
 1235 4366 4405 0.9931 0.9929
MDA-MB-231 Imatinib
1.11
uM
LJP6
 72
hr
 1235 4279 4405 0.9734 0.9713
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 1235 4334 4405 0.9851 0.9843
MDA-MB-231 Imatinib
10
uM
LJP6
 72
hr
 1235 4164 4405 0.9453 0.9396
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1235 3892 4405 0.8837 0.8696
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 72
hr
 1235 3542 4405 0.8051 0.7773
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 1235 2913 4405 0.6628 0.5978
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 72
hr
 1235 1814 4405 0.4128 0.2310
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1235 1283 4405 0.2919 0.0210
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 72
hr
 1235 382 4405 0.0872 -0.4731
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1235 3304 4660 0.7086 0.6698
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 1235 534 4405 0.1209 -0.3700
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 1235 773 4660 0.1654 -0.2206
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1235 506 4405 0.1147 -0.3866
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 1235 521 4660 0.1120 -0.3638
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 1235 459 4405 0.1041 -0.4182